Kim Na-Yeong, Chung Ki-Ho
Department of Preventive and Public Health Dentistry, Chonnam National University School of Dentistry, Gwangju, Republic of Korea.
Dental Science Research Institute, Chonnam National University, Gwangju, Republic of Korea.
Ren Fail. 2025 Dec;47(1):2531239. doi: 10.1080/0886022X.2025.2531239. Epub 2025 Jul 20.
Chronic kidney disease (CKD) and oral health are important public health problems worldwide, resulting in various complications. This study aimed to confirm the association between CKD and the number of teeth using data from the Korea National Health and Nutrition Examination Survey (KNHANES), which is representative of Korean adults. This study used raw data from the 6th and 7th (2013-2018) KNHANES and targeted 16,125 adults aged 40 years or older in Korea. Chronic kidney disease was defined as 2021 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). Multiple logistic regression analysis was used to examine the association between CKD and the number of teeth. The prevalence of CKD was significantly higher in the group with fewer than 20 teeth. In the multivariate logistic regression analysis, CKD was associated with having fewer than 20 teeth after adjusting for age, sex, household income, education, alcohol consumption, smoking, body mass index, hypertension, diabetes mellitus, angina, myocardial infarction, stroke, dyslipidemia, and performance of an oral examination within 1 year, daily toothbrushing frequency, and hygiene product use (Odds ratio = 1.34; 95% Confidence Interval = 1.03-1.74). Therefore, CKD may contribute to an increased risk of tooth loss. Implementing an integrated healthcare approach for oral health management in individuals with CKD could help reduce their burden of oral diseases.
慢性肾脏病(CKD)和口腔健康是全球重要的公共卫生问题,会导致各种并发症。本研究旨在利用韩国国家健康与营养检查调查(KNHANES)的数据,证实CKD与牙齿数量之间的关联,该调查数据代表了韩国成年人的情况。本研究使用了第六次和第七次(2013 - 2018年)KNHANES的原始数据,目标人群为韩国16,125名40岁及以上的成年人。慢性肾脏病按照2021年慢性肾脏病流行病学协作组(CKD - EPI)的标准定义。采用多元逻辑回归分析来检验CKD与牙齿数量之间的关联。牙齿少于20颗的人群中CKD的患病率显著更高。在多因素逻辑回归分析中,在调整了年龄、性别、家庭收入、教育程度、饮酒、吸烟、体重指数、高血压、糖尿病、心绞痛、心肌梗死、中风、血脂异常、1年内是否进行口腔检查、每日刷牙频率和卫生用品使用情况后,CKD与牙齿少于20颗有关(比值比 = 1.34;95%置信区间 = 1.03 - 1.74)。因此,CKD可能会增加牙齿脱落的风险。为CKD患者实施综合医疗保健方法进行口腔健康管理,有助于减轻他们的口腔疾病负担。