Quiet, Please-The Brain is Buzzing: Levetiracetam and the Paradox of (Fast) Ripples in Alzheimer's Disease.
作者信息
Marawar Rohit
机构信息
Department of Neurology,Wayne State University, Detroit, MI, USA.
出版信息
Epilepsy Curr. 2025 Jul 17:15357597251358411. doi: 10.1177/15357597251358411.
Abstract
摘要
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Quiet, Please-The Brain is Buzzing: Levetiracetam and the Paradox of (Fast) Ripples in Alzheimer's Disease.请安静——大脑在嗡嗡作响：左乙拉西坦与阿尔茨海默病中（快速）脑电波的悖论
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本文引用的文献
1
High-frequency oscillations in epileptic and non-epileptic Alzheimer's disease patients and the differential effect of levetiracetam on the oscillations.癫痫和非癫痫性阿尔茨海默病患者的高频振荡以及左乙拉西坦对振荡的不同作用。
Brain Commun. 2025 Feb 13;7(1):fcaf041. doi: 10.1093/braincomms/fcaf041. eCollection 2025.
2
Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer's disease and 5XFAD mice.癫痫发作使阿尔茨海默病和 5XFAD 小鼠中的兴奋性：抑制性失衡恶化。
Brain. 2024 Jun 3;147(6):2169-2184. doi: 10.1093/brain/awae126.
3
Effect of Levetiracetam on Cognition in Patients With Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial.左乙拉西坦对伴有和不伴有痫样活动的阿尔茨海默病患者认知功能的影响：一项随机临床试验。
JAMA Neurol. 2021 Nov 1;78(11):1345-1354. doi: 10.1001/jamaneurol.2021.3310.
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Systematic review of coexistent epileptic seizures and Alzheimer's disease: Incidence and prevalence.癫痫发作与阿尔茨海默病共存的系统评价：发病率和患病率。
J Am Geriatr Soc. 2021 Jul;69(7):2011-2020. doi: 10.1111/jgs.17101. Epub 2021 Mar 19.
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High-frequency oscillations: The state of clinical research.高频振荡：临床研究现状
Epilepsia. 2017 Aug;58(8):1316-1329. doi: 10.1111/epi.13829. Epub 2017 Jun 30.
6
Neuronal activity enhances tau propagation and tau pathology in vivo.神经元活动增强体内tau蛋白的传播和tau病理变化。
Nat Neurosci. 2016 Aug;19(8):1085-92. doi: 10.1038/nn.4328. Epub 2016 Jun 20.
7
Seizures and epileptiform activity in the early stages of Alzheimer disease.阿尔茨海默病早期的癫痫发作和癫痫样活动。
JAMA Neurol. 2013 Sep 1;70(9):1158-66. doi: 10.1001/jamaneurol.2013.136.
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High-frequency oscillations (HFOs) in clinical epilepsy.临床癫痫中的高频震荡（HFOs）。
Prog Neurobiol. 2012 Sep;98(3):302-15. doi: 10.1016/j.pneurobio.2012.03.001. Epub 2012 Apr 3.
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