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迈向用于脑实质病变减瘤的可操纵神经外科机器人

Towards a Steerable Neurosurgical Robot for Debulking of Brain Mass Lesions.

作者信息

Saini Sarvesh, Rezaeian Saeed, Akbari Arshia, Badie Behnam, Sheng Jun

机构信息

Department of Computer Science, University of Miami, Coral Gables, FL 33143 USA; School of Advanced Engineering, UPES, Dehradun, Uttarakhand 248007 India.

Department of Mechanical Engineering, University of California Riverside, Riverside, CA 92521, USA.

出版信息

IEEE Robot Autom Lett. 2025 May;10(5):4690-4697. doi: 10.1109/lra.2025.3548352. Epub 2025 Mar 5.

Abstract

Minimally invasive surgery is regarded as a safer approach than open craniotomy to removing deep intracerebral mass lesions such as hematomas. It is usually performed by introducing a straight suction tool, sometimes combined with accessories for tissue debridement and irrigation, into the brain. Since collateral trauma to healthy tissue is proportional to the diameter of the tools, slender tools with small diameters are desired. However, current minimally invasive tools are inadequate for removal of large, multi-focal, and fibrous mass lesions. In this work, we present a new robotic surgical device for removing intracerebral mass lesions. The device consists of four concentric tubes. From outermost to innermost, they include a straight rigid stainless steel tube, a precurved superelastic nitinol tube with asymmetric notches, a braid-reinforced composite tube with tissue cutting holes at the tip, and a suction tube connected with a suction machine. A Pebax sleeve covers the notched area of the outer tube except the two most distal notches. By rotating and translating the notched nitinol tube, the robot tip can be manipulated inside a mass lesion. By concurrently rotating the cutting tube and applying negative pressure, tissues can be cut and removed through the suction tube. In this paper, we present our design and fabrication of this robotic device, kinematic modeling of the robot in terms of the rotation and translation of the notched tube and rotation of the cutting tube, and the results of feasibility studies show 540% improvement of mass lesion removal efficiency.

摘要

与开颅手术相比,微创手术被认为是一种更安全的方法来切除深部脑内肿块病变,如血肿。它通常是通过将一个直的吸引工具,有时结合用于组织清创和冲洗的附件,引入大脑来进行的。由于对健康组织的附带创伤与工具的直径成正比,因此需要小直径的细长工具。然而,目前的微创工具在去除大的、多灶性的和纤维性肿块病变方面存在不足。在这项工作中,我们提出了一种用于切除脑内肿块病变的新型机器人手术设备。该设备由四个同心管组成。从最外层到最内层,它们包括一个直的刚性不锈钢管、一个带有不对称切口的预弯曲超弹性镍钛诺管、一个在尖端带有组织切割孔的编织增强复合管以及一个与抽吸机相连的吸液管。一个聚醚嵌段酰胺套管覆盖外管的切口区域,但不包括最远端的两个切口。通过旋转和平移有切口的镍钛诺管,可以在肿块病变内部操纵机器人尖端。通过同时旋转切割管并施加负压,可以通过吸液管切割和去除组织。在本文中,我们介绍了这种机器人设备的设计和制造、根据有切口管的旋转和平移以及切割管的旋转对机器人进行的运动学建模,以及可行性研究结果,结果表明肿块病变切除效率提高了540%。

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本文引用的文献

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Minimally Invasive Intracerebral Hemorrhage Evacuation: A review.微创颅内血肿清除术:综述。
Ann Biomed Eng. 2022 Apr;50(4):365-386. doi: 10.1007/s10439-022-02934-z. Epub 2022 Feb 28.
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