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火激红斑:烤焦皮肤综合征作为慢性疼痛的皮肤标志物

Erythema Ab Igne: Toasted Skin Syndrome as a Cutaneous Marker of Chronic Pain.

作者信息

Mahmood Nuha, Pinheiro Alves Alana, Melgar Thomas A

机构信息

Internal Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, USA.

Infectious Disease, Henry Ford Health, Detroit, USA.

出版信息

Cureus. 2025 Jun 17;17(6):e86243. doi: 10.7759/cureus.86243. eCollection 2025 Jun.

DOI:10.7759/cureus.86243
PMID:40688945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12275499/
Abstract

Erythema ab igne (EAI) is a rare skin reaction caused by prolonged exposure to low-level heat, resulting in a reticular pattern of localized erythema and hyperpigmentation. This condition carries a potential risk of transformation into cutaneous malignancy. We present the case of a 38-year-old woman who developed a reticular-patterned rash on her abdomen. She had been using hot water bags to alleviate severe abdominal pain associated with chronic cholecystitis, which led to the development of hyperpigmented, mottled, erythematous skin changes across her entire abdomen. After discontinuing heat application, her hyperpigmentation significantly decreased, although the skin changes persisted years later.

摘要

火激红斑(EAI)是一种罕见的皮肤反应,由长期暴露于低水平热量引起,导致局部红斑和色素沉着呈网状分布。这种情况有转化为皮肤恶性肿瘤的潜在风险。我们报告一例38岁女性病例,该患者腹部出现网状皮疹。她一直在使用热水袋缓解与慢性胆囊炎相关的严重腹痛,这导致她整个腹部出现色素沉着、斑驳、红斑性皮肤改变。停止热敷后,她的色素沉着明显减轻,尽管多年后皮肤改变仍持续存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/119a/12275499/7a1555ad0831/cureus-0017-00000086243-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/119a/12275499/09440861d8f3/cureus-0017-00000086243-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/119a/12275499/7a1555ad0831/cureus-0017-00000086243-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/119a/12275499/09440861d8f3/cureus-0017-00000086243-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/119a/12275499/7a1555ad0831/cureus-0017-00000086243-i02.jpg

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本文引用的文献

1
Erythema ab igne: Toasted Skin Syndrome.火激红斑:烤焦皮肤综合征。
HCA Healthc J Med. 2021 Apr 28;2(2):97-100. doi: 10.36518/2689-0216.1149. eCollection 2021.
2
Malignant transformation of erythema ab igne.火激红斑的恶性转化
JAAD Case Rep. 2022 Jul 5;26:85-87. doi: 10.1016/j.jdcr.2022.06.018. eCollection 2022 Aug.
3
Self-applied topical interventions for melasma: a systematic review and meta-analysis of data from randomized, investigator-blinded clinical trials.自用眼霜治疗黄褐斑:一项随机、研究者设盲临床试验数据的系统评价和荟萃分析。
Br J Dermatol. 2022 Sep;187(3):309-317. doi: 10.1111/bjd.21244. Epub 2022 May 18.
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Erythema ab igne with features resembling keratosis lichenoides chronica.火激红斑,表现类似慢性苔藓样糠疹角化病。
J Cutan Pathol. 2021 Jan;48(1):151-153. doi: 10.1111/cup.13885. Epub 2020 Nov 5.
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Erythema Ab Igne due to Heating Pad Use: A Case Report and Review of Clinical Presentation, Prevention, and Complications.因使用加热垫导致的火激红斑:一例病例报告及临床表现、预防和并发症的综述
Case Rep Med. 2016;2016:1862480. doi: 10.1155/2016/1862480. Epub 2016 Jan 3.
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Erythema ab igne secondary to repeated heating pad use: an image case.因反复使用加热垫导致的火激红斑:一例影像学病例
J Community Hosp Intern Med Perspect. 2015 Sep 1;5(4):28335. doi: 10.3402/jchimp.v5.28335. eCollection 2015.
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Erythema ab igne.火激红斑
Dermatol Online J. 2011 Oct 15;17(10):28.
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Chronic heat-induced skin lesions (erythema ab Igne): ultrastructural studies.慢性热致皮肤病变(火激红斑):超微结构研究
Ultrastruct Pathol. 2001 Mar-Apr;25(2):93-7.