Bashir Fazari Atif, Javid Ufwana, Fahad Asma, AlSuwaidi Shaima, Nikhat Fareeda
Obstetrics and Gynecology, Latifa Hospital, Dubai Health, Dubai, ARE.
Obstetrics and Gynecology, Dubai Health, Dubai, ARE.
Cureus. 2025 Jun 18;17(6):e86271. doi: 10.7759/cureus.86271. eCollection 2025 Jun.
Placenta accreta spectrum (PAS) refers to a group of disorders characterized by abnormal trophoblastic invasion of the uterine wall, which can result in life-threatening complications such as severe hemorrhage and the need for hysterectomy. A 30-year-old female patient with a history of two prior cesarean sections and diagnosed with Grade IV placenta previa at 34+0 weeks gestation was referred to our hospital for management. The patient presented with antepartum hemorrhage and was at elevated risk for PAS due to her previous cesarean sections and placenta previa. Ultrasound findings suggested PAS, including hypervascularity, consistent with trophoblastic invasion. Elective cesarean section was performed, and intraoperatively, focal accreta was identified with manual removal of the placenta and bilateral uterine artery ligation to control hemorrhage. Histopathology confirmed myometrial tissue with hemorrhage and dilated blood vessels, consistent with PAS, but without evidence of malignancy. The patient was managed in a multidisciplinary setting and received postoperative care for bleeding complications related to Factor 12 deficiency. Her recovery was uneventful, and she was discharged on postoperative day 3. This case highlights the importance of early diagnosis, imaging, and multidisciplinary management in optimizing maternal and fetal outcomes in PAS.
胎盘植入谱系疾病(PAS)是指一组以滋养细胞异常侵入子宫壁为特征的疾病,可导致严重出血和子宫切除等危及生命的并发症。一名30岁女性患者,有两次剖宫产史,妊娠34+0周时诊断为IV级前置胎盘,转诊至我院治疗。患者出现产前出血,由于既往剖宫产史和前置胎盘,发生PAS的风险升高。超声检查结果提示PAS,包括血管增多,符合滋养细胞侵入表现。行择期剖宫产,术中发现局灶性植入,手动剥离胎盘并结扎双侧子宫动脉以控制出血。组织病理学证实为子宫肌层组织伴出血和血管扩张,符合PAS,但无恶性证据。患者在多学科团队管理下接受治疗,针对与凝血因子12缺乏相关的出血并发症进行术后护理。她恢复顺利,术后第3天出院。该病例强调了早期诊断、影像学检查和多学科管理对于优化PAS患者母婴结局的重要性。