Page Malcolm G P
University of Basel, Basel, Switzerland.
Antimicrob Agents Chemother. 2025 Aug 6;69(8):e0056225. doi: 10.1128/aac.00562-25. Epub 2025 Jul 21.
A standardized scheme for numbering and annotation of secondary structure features has been proposed for class D β-lactamases (F. Attana, S. Kim, J. Spencer, B. I. Iorga, et al., Antimicrob Agents Chemother 69:e00150-25, 2025, https://doi.org/10.1128/aac.00150-25). This will significantly facilitate the comparison of biochemical and biophysical studies performed on the disparate members of this class of enzymes and improve communication in the field.
已针对D类β-内酰胺酶提出了一种用于二级结构特征编号和注释的标准化方案(F. 阿塔纳、S. 金、J. 斯宾塞、B. I. 约尔加等人,《抗菌剂与化疗》69: e00150 - 25, 2025, https://doi.org/10.1128/aac.00150 - 25)。这将极大地促进对这类酶不同成员进行的生化和生物物理研究的比较,并改善该领域的交流。