Gennari C, Nami R, Bianchini C, Aversa A M
Miner Electrolyte Metab. 1985;11(6):369-73.
The effect of acute hypercalcemia on blood pressure and plasma catecholamine levels was investigated in 10 normal subjects and in 5 patients completely thyroparathyroidectomized (TPTX) for a parathyroid cancer. In normal subjects, calcium infusion (15 mg/kg over 3 h) significantly increased plasma calcium and epinephrine levels and blood pressure. Plasma norepinephrine was increased only after 3 h of calcium infusion. In TPTX patients, calcium infusion increased significantly plasma calcium and epinephrine but not blood pressure. The percent increase in mean blood pressure during calcium infusion correlated with the concomitant percent increase in serum calcium in normal subjects (r = 0.71, p less than 0.001) but not in TPTX patients (r = -0.08). These data are in agreement with the hypothesis that the effect of calcium on arterial pressure is realized under intact parathyroid function.
研究了急性高钙血症对10名正常受试者和5名因甲状旁腺癌而完全甲状旁腺切除（TPTX）患者的血压和血浆儿茶酚胺水平的影响。在正常受试者中，输注钙（3小时内输注15mg/kg）显著提高了血浆钙、肾上腺素水平和血压。仅在输注钙3小时后，血浆去甲肾上腺素才升高。在TPTX患者中，输注钙显著提高了血浆钙和肾上腺素水平，但未升高血压。正常受试者在输注钙期间平均血压的升高百分比与血清钙的相应升高百分比相关（r = 0.71，p < 0.001），而TPTX患者则无此相关性（r = -0.08）。这些数据与以下假设一致，即钙对动脉血压的影响是在甲状旁腺功能完整的情况下实现的。
