Satdhabudha Opas, Songvasin Manita, Chaumrattanakul Utairat, Kantasiripitak Charinee
Division of Cardiothoracic Surgery, Department of Surgery, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand.
Department of Radiology, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand.
J Cardiothorac Surg. 2025 Jul 21;20(1):309. doi: 10.1186/s13019-025-03533-4.
In our institute, resection and aortic anastomosis for newborns and infants with coarctation of the aorta are typically performed using continuous nonabsorbable (polypropylene) sutures. This cross-sectional survey aims to examine the anastomosis site, focusing on the prevalence of growth and its correlation with recoarctation in cases requiring surgical reintervention.
Patients who underwent aortic anastomosis for symptomatic coarctation during their first year of life between 2008 and 2023 and were still alive were included in the study for evaluation. Aortic arch diameters were assessed using computed tomography angiography (CTA), and z-scores were calculated. For patients with recurrent stenosis who required subsequent surgery, the surgical pathology was reviewed.
A total of 15 patients underwent CTA assessment, with a median time from surgery to CTA of 8.08 years (4.39, 10.02). The z-scores for the diameters at the repaired areas were as follows: for the distal transverse arch, the median z-score was - 0.08 (-0.52, 0.59), and for the descending aorta at the anastomosis, it was 1.13 (0.18, 1.72). When comparing the two subgroups-7 patients with aortic arch hypoplasia and 8 without-no significant differences were found in the z-scores of the diameters at the repaired sites. In one case of restenosis at the 4-year follow-up, subsequent surgery revealed that the suture line did not align with the narrowest segment.
Using continuous non-absorbable suture for aortic anastomosis in coarctation repair for newborns and infants can result in the growth of the aortic arch and the anastomosis site reaching the normal range, regardless of the presence of aortic arch hypoplasia. Pathological findings from a surgical reintervention indicate that the aortic wall segment containing suture material does not align with the area exhibiting the greatest narrowing.
Trial registration number (Study ID): TCTR20240412007.
在我们研究所,对于患有主动脉缩窄的新生儿和婴儿,主动脉切除和吻合术通常使用连续不可吸收(聚丙烯)缝线进行。这项横断面调查旨在检查吻合部位,重点关注生长情况的发生率及其与需要手术再次干预病例中再缩窄的相关性。
纳入2008年至2023年期间在出生后第一年内因有症状的主动脉缩窄接受主动脉吻合术且仍存活的患者进行评估。使用计算机断层血管造影(CTA)评估主动脉弓直径,并计算z评分。对于需要后续手术的复发性狭窄患者,回顾手术病理。
共有15例患者接受CTA评估,从手术到CTA的中位时间为8.08年(4.39,10.02)。修复部位直径的z评分如下:对于远端横弓,中位z评分为-0.08(-0.52,0.59),对于吻合处的降主动脉,为1.13(0.18,1.72)。比较两个亚组——7例主动脉弓发育不全患者和8例无主动脉弓发育不全患者——修复部位直径的z评分无显著差异。在4年随访中的1例再狭窄病例中,后续手术显示缝线位置与最狭窄段不一致。
在新生儿和婴儿主动脉缩窄修复中使用连续不可吸收缝线进行主动脉吻合术,可使主动脉弓和吻合部位生长至正常范围,无论是否存在主动脉弓发育不全。手术再次干预的病理结果表明,含有缝线材料的主动脉壁段与显示最大狭窄的区域不一致。
试验注册号(研究ID):TCTR20240412007。