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可吸收聚二氧六环酮缝线与完全性肺静脉异位连接的结果。

Absorbable polydioxanone suture and results in total anomalous pulmonary venous connection.

作者信息

Hawkins J A, Minich L L, Tani L Y, Ruttenberg H D, Sturtevant J E, McGough E C

机构信息

Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, USA.

出版信息

Ann Thorac Surg. 1995 Jul;60(1):55-9.

PMID:7598621
Abstract

BACKGROUND

Despite theoretical advantages of absorbable suture in the growing vascular anastomosis, there has not been a documented advantage over nonabsorbable suture in preventing late anastomotic stenosis in total anomalous pulmonary venous connection (TAPVC).

METHODS

We reviewed our experience from 1982 to 1994 with 65 hospital survivors of total TAPVC repair to examine the influence of suture type on survival and incidence of late pulmonary venous obstruction. From 1982 until 1988, we used continuous nonabsorbable polypropylene suture for the pulmonary venous-left atrial anastomosis in supracardiac, infracardiac, and mixed types of TAPVC: In 1989, we adopted a running absorbable polydioxanone suture technique. Cardiac catheterization and echocardiography were used to evaluate late pulmonary venous obstruction.

RESULTS

Late pulmonary venous obstruction occurred in 17% (4/23) of survivors after repair with polypropylene suture compared with 3.2% (1/32) after repair with polydioxanone suture (p < 0.05). There were no instances of late pulmonary venous obstruction in the intracardiac TAPVC group (0/10). All late pulmonary venous obstructions occurred within 16 months after operation. The actuarial 3-year and 5-year freedom from late pulmonary venous obstruction was 100% for intracardiac TAPVC, 96% for the polydioxanone group, and 81% for the polypropylene group. Five patients died late (5/65, 7.7%), 3 in the polypropylene suture group (3/23, 13%) and 2 in the polydioxanone group (2/32, 6%).

CONCLUSIONS

Continuous absorbable polydioxanone suture for the repair of TAPVC results in a low incidence of late pulmonary venous obstruction and death and appears to offer advantages over a continuous nonabsorbable suture. A continuous nonabsorbable suture may limit growth of a vascular anastomosis, particularly one involving a "low-pressure" anastomosis such as in the repair of TAPVC:

摘要

背景

尽管可吸收缝线在生长中的血管吻合方面具有理论优势,但在完全性肺静脉异位连接(TAPVC)的晚期吻合口狭窄预防方面,尚无文献证明其优于不可吸收缝线。

方法

我们回顾了1982年至1994年期间65例TAPVC修复术后存活的住院患者的经验,以研究缝线类型对生存率和晚期肺静脉梗阻发生率的影响。从1982年到1988年,我们在心上型、心下型和混合型TAPVC的肺静脉-左心房吻合术中使用连续不可吸收聚丙烯缝线;1989年,我们采用了连续可吸收聚二氧六环酮缝线技术。通过心脏导管检查和超声心动图评估晚期肺静脉梗阻情况。

结果

聚丙烯缝线修复术后的存活者中,17%(4/23)发生晚期肺静脉梗阻,而聚二氧六环酮缝线修复术后为3.2%(1/32)(p<0.05)。心内型TAPVC组未发生晚期肺静脉梗阻(0/10)。所有晚期肺静脉梗阻均发生在术后16个月内。心内型TAPVC的3年和5年无晚期肺静脉梗阻生存率为100%,聚二氧六环酮组为96%,聚丙烯组为81%。5例患者晚期死亡(5/65,7.7%),聚丙烯缝线组3例(3/23,13%),聚二氧六环酮组2例(2/32,6%)。

结论

连续可吸收聚二氧六环酮缝线用于TAPVC修复可降低晚期肺静脉梗阻和死亡的发生率,似乎比连续不可吸收缝线更具优势。连续不可吸收缝线可能会限制血管吻合口的生长,尤其是涉及“低压”吻合口的情况,如TAPVC修复术中:

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