球组合训练计划联合cTBS干预对自闭症谱系障碍儿童运动障碍的影响。
Effects of ball combination training program combined with cTBS intervention on motor disorder in children with autism spectrum disorder.
作者信息
Qi Kai, Sun Zhiyuan, Shi Yifan, Xiong Xuan, Liu Yufei, Cai Kelong, Chen Aiguo, Białas Marcin
机构信息
Gdansk University of Physical Education and Sport, Gdansk, 80-336, Poland.
Yangzhou University, Yangzhou, Yangzhou, 225009, China.
出版信息
Sci Rep. 2025 Jul 21;15(1):26418. doi: 10.1038/s41598-025-11540-7.
UNLABELLED
Purpose In children with Autism Spectrum Disorder (ASD), motor disorders (MD) are a common occurrence, and developing effective interventions continues to be challenging. This study aims to investigate the effects of a 12-week ball combination training program (BCTP) combined with continuous theta burst stimulation (cTBS) on MD in children with ASD.
METHODS
The study employed a 4 (cTBS, BCTP, cTBS*BCTP, control group) × 2 (pre-test, post-test) mixed design methodology. 50 participants were allocated to three experimental groups(38) and one control group(12), receiving interventions for a period of 12 weeks. MD were measured using the Movement Assessment Battery for Children - Second Edition (MABC-2).
RESULTS
Results indicated that the cTBSBCTP group significantly improved the overall MABC-2 scores (P < 0.05) and Manual dexterity scores (P < 0.05) in children with ASD, and the BCTP group also significantly improved overall MABC-2 scores. Compared to the control group, the effect size for the cTBSBCTP group was 1.03 (95% CI: 0.13 to 1.94), showing the best intervention effect, outperforming the BCTP group (effect size: 0.82, 95% CI: -0.09 to 1.72) and the cTBS group (effect size: 0.43, 95% CI: -0.38 to 1.23).
CONCLUSION
Overall, the BCTP*cTBS group showed the most significant intervention effects across various dimensions, demonstrating the efficacy of combined interventions in improving MD in children with ASD, confirming that combined interventions are superior to single interventions.
未标注
目的 在自闭症谱系障碍（ASD）儿童中，运动障碍（MD）很常见，开发有效的干预措施仍然具有挑战性。本研究旨在探讨为期12周的球类组合训练计划（BCTP）联合连续theta爆发刺激（cTBS）对ASD儿童运动障碍的影响。
方法
本研究采用4（cTBS、BCTP、cTBS*BCTP、对照组）×2（预测试、后测试）混合设计方法。50名参与者被分配到三个实验组（38名）和一个对照组（12名），接受为期12周的干预。使用儿童运动评估量表第二版（MABC-2）测量运动障碍。
结果
结果表明，cTBSBCTP组显著提高了ASD儿童的整体MABC-2评分（P < 0.05）和手动灵巧性评分（P < 0.05），BCTP组也显著提高了整体MABC-2评分。与对照组相比，cTBSBCTP组的效应量为1.03（95%CI：0.13至1.94），显示出最佳的干预效果，优于BCTP组（效应量：0.82，95%CI：-0.09至1.72）和cTBS组（效应量：0.43，95%CI：-0.38至1.23）。
结论
总体而言，BCTP*cTBS组在各个维度上显示出最显著的干预效果，证明了联合干预在改善ASD儿童运动障碍方面的有效性，证实联合干预优于单一干预。
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