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本文引用的文献

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Train-your-brain program to reduce depression, anxiety, and stress in stroke survivors: a pilot community-based cognitive intervention study.训练大脑计划以减轻中风幸存者的抑郁、焦虑和压力:一项基于社区的认知干预试点研究
Front Neurol. 2023 Aug 10;14:1163094. doi: 10.3389/fneur.2023.1163094. eCollection 2023.
2
Cognitive Impairment After Ischemic and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association/American Stroke Association.《缺血性卒中和出血性卒中后的认知障碍:美国心脏协会/美国卒中协会的科学声明》
Stroke. 2023 Jun;54(6):e272-e291. doi: 10.1161/STR.0000000000000430. Epub 2023 May 1.
3
Rehabilitation of Cognitive Deficits Poststroke: Systematic Review and Meta-Analysis of Randomized Controlled Trials.中风后认知缺陷的康复:随机对照试验的系统评价和荟萃分析
Stroke. 2022 May;53(5):1700-1710. doi: 10.1161/STROKEAHA.121.034218. Epub 2022 Feb 3.
4
A prospective cohort study on longitudinal trajectories of cognitive function after stroke.一项关于卒中后认知功能纵向轨迹的前瞻性队列研究。
Sci Rep. 2021 Aug 26;11(1):17271. doi: 10.1038/s41598-021-96347-y.
5
Association of White Matter Hyperintensities and Cardiovascular Disease: The Importance of Microcirculatory Disease.脑白质高信号与心血管疾病的关联:微循环疾病的重要性。
Circ Cardiovasc Imaging. 2020 Aug;13(8):e010460. doi: 10.1161/CIRCIMAGING.120.010460. Epub 2020 Jul 28.
6
Cognition in Stroke Rehabilitation and Recovery Research: Consensus-Based Core Recommendations From the Second Stroke Recovery and Rehabilitation Roundtable.脑卒中康复与恢复研究中的认知:第二届脑卒中恢复与康复圆桌会议达成的基于共识的核心建议。
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7
Addressing cognitive impairment following stroke: systematic review and meta-analysis of non-randomised controlled studies of psychological interventions.针对脑卒中后认知障碍的心理干预:非随机对照研究的系统评价和荟萃分析。
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8
Systematic Review and Meta-Analysis of Prevalence in Post-Stroke Neurocognitive Disorders in Hospital-Based Studies.基于医院研究的中风后神经认知障碍患病率的系统评价与荟萃分析。
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9
Elderly Stroke Rehabilitation: Overcoming the Complications and Its Associated Challenges.老年中风康复:克服并发症及其相关挑战。
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10
General and Domain-Specific Effectiveness of Cognitive Remediation after Stroke: Systematic Literature Review and Meta-Analysis.脑卒中后认知康复的一般和特定领域效果:系统文献回顾和荟萃分析。
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中风后基于社区的“训练你的大脑”试点干预:10个月随访期间的认知轨迹

Train-your-brain pilot community-based intervention after stroke: cognitive trajectory over 10-month follow-up.

作者信息

Chen Nicole Yun Ching, Tham Xiang Cong, Dong Yanhong

机构信息

Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Alice Lee Centre for Nursing Studies, National University of Singapore, Singapore, Singapore.

出版信息

Front Neurol. 2025 Jul 7;16:1500943. doi: 10.3389/fneur.2025.1500943. eCollection 2025.

DOI:10.3389/fneur.2025.1500943
PMID:40692558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12277129/
Abstract

INTRODUCTION

Stroke leads to cognitive impairments that affect survivors' quality of life. This study aimed to assess the effectiveness of the Train-Your-Brain (TYB) pilot community intervention in cognitive outcomes among stroke survivors and caregivers at baseline, post-intervention, and 10-month follow-up.

METHODS

Thirty-one participants (20 stroke survivors, 11 caregivers) were evaluated. Cognitive functioning was measured using the Montreal Cognitive Assessment (MoCA) with analysis of subtest-level performances and Symbol Digit Modalities Test (SDMT).

RESULTS

Among stroke survivors, MoCA immediate recall scores maintained during the intervention, but declined 10-months later ( = 0.005). Analysis of the MoCA delayed memory subtest revealed a graded performance across different recall formats. Free recall and category-cued recall deteriorated over 10 months, while multiple-choice format recall remained stable. A slight improvement was observed in SDMT scores from pre-TYB to post-TYB, which was relatively maintained after 10 months. Caregivers demonstrated significant improvements in MoCA language and sentence repetition ( = 0.014) scores at 10-month follow-up.

CONCLUSION

Our findings suggest that while the intervention may lead to short-term stabilization in cognitive functioning among stroke survivors, these gains may not be sustained over time. Persistent cognitive deficits underscore the need for ongoing and long-term support.

摘要

引言

中风会导致认知障碍,影响幸存者的生活质量。本研究旨在评估“训练你的大脑”(TYB)社区干预试点对中风幸存者及其照顾者在基线、干预后和10个月随访时认知结果的有效性。

方法

对31名参与者(20名中风幸存者,11名照顾者)进行了评估。使用蒙特利尔认知评估量表(MoCA)测量认知功能,并分析各子测试水平的表现以及符号数字模态测试(SDMT)。

结果

在中风幸存者中,MoCA即时回忆分数在干预期间保持稳定,但在10个月后下降(P = 0.005)。对MoCA延迟记忆子测试的分析显示,不同回忆形式的表现呈梯度变化。自由回忆和类别线索回忆在10个月内恶化,而多项选择形式的回忆保持稳定。从TYB前到TYB后,SDMT分数略有改善,10个月后相对保持稳定。照顾者在10个月随访时,MoCA语言和句子重复(P = 0.014)分数有显著改善。

结论

我们的研究结果表明,虽然该干预可能会使中风幸存者的认知功能在短期内稳定,但这些改善可能不会随着时间的推移而持续。持续存在的认知缺陷凸显了持续和长期支持的必要性。