Chen Nicole Yun Ching, Tham Xiang Cong, Dong Yanhong
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Alice Lee Centre for Nursing Studies, National University of Singapore, Singapore, Singapore.
Front Neurol. 2025 Jul 7;16:1500943. doi: 10.3389/fneur.2025.1500943. eCollection 2025.
Stroke leads to cognitive impairments that affect survivors' quality of life. This study aimed to assess the effectiveness of the Train-Your-Brain (TYB) pilot community intervention in cognitive outcomes among stroke survivors and caregivers at baseline, post-intervention, and 10-month follow-up.
Thirty-one participants (20 stroke survivors, 11 caregivers) were evaluated. Cognitive functioning was measured using the Montreal Cognitive Assessment (MoCA) with analysis of subtest-level performances and Symbol Digit Modalities Test (SDMT).
Among stroke survivors, MoCA immediate recall scores maintained during the intervention, but declined 10-months later ( = 0.005). Analysis of the MoCA delayed memory subtest revealed a graded performance across different recall formats. Free recall and category-cued recall deteriorated over 10 months, while multiple-choice format recall remained stable. A slight improvement was observed in SDMT scores from pre-TYB to post-TYB, which was relatively maintained after 10 months. Caregivers demonstrated significant improvements in MoCA language and sentence repetition ( = 0.014) scores at 10-month follow-up.
Our findings suggest that while the intervention may lead to short-term stabilization in cognitive functioning among stroke survivors, these gains may not be sustained over time. Persistent cognitive deficits underscore the need for ongoing and long-term support.
中风会导致认知障碍,影响幸存者的生活质量。本研究旨在评估“训练你的大脑”(TYB)社区干预试点对中风幸存者及其照顾者在基线、干预后和10个月随访时认知结果的有效性。
对31名参与者(20名中风幸存者,11名照顾者)进行了评估。使用蒙特利尔认知评估量表(MoCA)测量认知功能,并分析各子测试水平的表现以及符号数字模态测试(SDMT)。
在中风幸存者中,MoCA即时回忆分数在干预期间保持稳定,但在10个月后下降(P = 0.005)。对MoCA延迟记忆子测试的分析显示,不同回忆形式的表现呈梯度变化。自由回忆和类别线索回忆在10个月内恶化,而多项选择形式的回忆保持稳定。从TYB前到TYB后,SDMT分数略有改善,10个月后相对保持稳定。照顾者在10个月随访时,MoCA语言和句子重复(P = 0.014)分数有显著改善。
我们的研究结果表明,虽然该干预可能会使中风幸存者的认知功能在短期内稳定,但这些改善可能不会随着时间的推移而持续。持续存在的认知缺陷凸显了持续和长期支持的必要性。