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建立并应用于接受持续肾脏替代治疗患者的感染预防与控制体系。

Establishment and application of an infection prevention and control system for patients undergoing continuous renal replacement therapy.

作者信息

Zhao Zhongjing, Zhao Huijie, Yang Yang, Wang Yuncong, Zhao Xia

机构信息

Division of Healthcare-Associated Infection Management, Xuanwu Hospital, Capital Medical University, Beijing, China.

出版信息

Front Med (Lausanne). 2025 Jul 7;12:1506188. doi: 10.3389/fmed.2025.1506188. eCollection 2025.

Abstract

BACKGROUND

Continuous renal replacement therapy (CRRT) is essential for critically ill patients but carries a high risk of hospital-acquired infections. Implementing an effective infection prevention and control system is critical for improving patient safety.

METHODS

This study utilized the Delphi method to develop a comprehensive infection prevention and control indicator system specifically designed for CRRT patients. A total of 126 patients treated at Xuanwu Hospital, Capital Medical University from January to December 2023 were included in the study. They were divided into a control group ( = 62), which received standard care, and an observation group ( = 64), which adopted the newly developed indicator system. Adverse event rates and nursing quality scores were compared between the two groups.

RESULTS

The final indicator system consisted of 3 primary, 9 secondary, and 27 tertiary indicators, with expert consensus reflected by a reliability coefficient of 0.795. The observation group demonstrated a significantly lower incidence of adverse events (3.12% vs. 16.12%, < 0.05) and higher nursing quality scores across three dimensions (basic care, equipment management, and nursing safety) compared to the control group ( < 0.05).

CONCLUSION

The infection prevention and control indicator system for CRRT patients exhibited strong reliability and scientific validity. Its implementation led to a significant reduction in infection rates and improvements in nursing quality, highlighting its potential for broader clinical adoption.

摘要

背景

连续性肾脏替代治疗(CRRT)对危重症患者至关重要,但存在医院获得性感染的高风险。实施有效的感染预防与控制体系对于提高患者安全至关重要。

方法

本研究采用德尔菲法制定了专门针对CRRT患者的综合感染预防与控制指标体系。纳入了2023年1月至12月在首都医科大学宣武医院接受治疗的126例患者。将他们分为对照组(n = 62),接受标准护理,以及观察组(n = 64),采用新制定的指标体系。比较两组的不良事件发生率和护理质量评分。

结果

最终的指标体系由3个一级指标、9个二级指标和27个三级指标组成,可靠性系数为0.795反映了专家共识。与对照组相比,观察组的不良事件发生率显著更低(3.12%对16.12%,P < 0.05),并且在三个维度(基础护理、设备管理和护理安全)上的护理质量评分更高(P < 0.05)。

结论

CRRT患者感染预防与控制指标体系具有很强的可靠性和科学有效性。其实施导致感染率显著降低和护理质量提高,凸显了其在更广泛临床应用中的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f304/12277335/9d828dee5824/fmed-12-1506188-g001.jpg

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