Zhao Zhongjing, Zhao Huijie, Yang Yang, Wang Yuncong, Zhao Xia
Division of Healthcare-Associated Infection Management, Xuanwu Hospital, Capital Medical University, Beijing, China.
Front Med (Lausanne). 2025 Jul 7;12:1506188. doi: 10.3389/fmed.2025.1506188. eCollection 2025.
Continuous renal replacement therapy (CRRT) is essential for critically ill patients but carries a high risk of hospital-acquired infections. Implementing an effective infection prevention and control system is critical for improving patient safety.
This study utilized the Delphi method to develop a comprehensive infection prevention and control indicator system specifically designed for CRRT patients. A total of 126 patients treated at Xuanwu Hospital, Capital Medical University from January to December 2023 were included in the study. They were divided into a control group ( = 62), which received standard care, and an observation group ( = 64), which adopted the newly developed indicator system. Adverse event rates and nursing quality scores were compared between the two groups.
The final indicator system consisted of 3 primary, 9 secondary, and 27 tertiary indicators, with expert consensus reflected by a reliability coefficient of 0.795. The observation group demonstrated a significantly lower incidence of adverse events (3.12% vs. 16.12%, < 0.05) and higher nursing quality scores across three dimensions (basic care, equipment management, and nursing safety) compared to the control group ( < 0.05).
The infection prevention and control indicator system for CRRT patients exhibited strong reliability and scientific validity. Its implementation led to a significant reduction in infection rates and improvements in nursing quality, highlighting its potential for broader clinical adoption.
连续性肾脏替代治疗（CRRT）对危重症患者至关重要，但存在医院获得性感染的高风险。实施有效的感染预防与控制体系对于提高患者安全至关重要。
本研究采用德尔菲法制定了专门针对CRRT患者的综合感染预防与控制指标体系。纳入了2023年1月至12月在首都医科大学宣武医院接受治疗的126例患者。将他们分为对照组（n = 62），接受标准护理，以及观察组（n = 64），采用新制定的指标体系。比较两组的不良事件发生率和护理质量评分。
最终的指标体系由3个一级指标、9个二级指标和27个三级指标组成，可靠性系数为0.795反映了专家共识。与对照组相比，观察组的不良事件发生率显著更低（3.12%对16.12%，P < 0.05），并且在三个维度（基础护理、设备管理和护理安全）上的护理质量评分更高（P < 0.05）。
CRRT患者感染预防与控制指标体系具有很强的可靠性和科学有效性。其实施导致感染率显著降低和护理质量提高，凸显了其在更广泛临床应用中的潜力。
