Volpe B T, Petito C K
Neurology. 1985 Dec;35(12):1793-7. doi: 10.1212/wnl.35.12.1793.
Neuropathologic examination of two patients with dementia showed chronic bilateral medial temporal lobe ischemic damage that included the hippocampus (particularly the CA-1 region), subiculum, and amygdala. Both patients had several myocardial infarctions, and the relatively circumscribed cerebral injury may have resulted from one or more episodes of global hypoxic ischemia. Focal hippocampal injury has been associated with amnesia. The additional damage to medial temporal lobe structures may have caused the dementia.
对两名痴呆患者的神经病理学检查显示，双侧内侧颞叶存在慢性缺血性损伤，累及海马体（尤其是CA-1区）、下托和杏仁核。两名患者均有多次心肌梗死，相对局限的脑损伤可能是由一次或多次全身性缺氧缺血发作所致。海马体局灶性损伤与失忆有关。内侧颞叶结构的额外损伤可能导致了痴呆。
