Ashmore Sarah, Steinbeck Abigail, Scioscia Nicholas, Weaver Ashlee, Sassani Jessica C
Section of Urogynecology and Reconstructive Pelvic Surgery, University of Chicago, 1217 N California Ave, Apt 1W, Chicago, IL, 60622, USA.
Department of Obstetrics and Gynecology, West Penn Hospital, Pittsburgh, PA, USA.
Int Urogynecol J. 2025 Jul 22. doi: 10.1007/s00192-025-06209-8.
There is limited literature regarding concomitant initiation of pelvic floor physical therapy (PFPT) and medications for overactive bladder treatment. PFPT improves patient symptoms, although adherence tends to be low. This retrospective cohort study assessed PFPT adherence of female patients with overactive bladder at a tertiary care center who were referred to PFPT. We hypothesized that concomitant PFPT and medication would correlate with decreased PFPT adherence among patients with overactive bladder.
Adherence to PFPT (defined as ≥ 50% attendance of the recommended sessions) was compared in patients with (PT + Med group) and in those without (PT group) concomitant medication prescription.
We evaluated 346 patients, with 196 in the PT group and 150 in the PT + Med group. The PT + Med group had a higher body mass index (30.0 kg/m vs 27.5 kg/m, p < 0.001), a higher rate of diabetes (20.7% vs 11.7%, p = 0.02), and higher urogenital distress inventory scores at baseline (p < 0.001). The PT group completed more PT sessions (p < 0.001) and was more likely to be adherent (30.6% vs 15.3%, p < 0.001). The PT + Med group was more likely to progress to minimally invasive therapy (10.0% vs 4.1%, p = 0.03). On multivariable logistic regression model, PFPT adherence remained significantly lower for the PT + Med group when controlling for comorbidities (adjusted OR 0.38, p = 0.001).
The addition of medication at the time of PFPT referral was associated with decreased PFPT adherence in overactive bladder patients.
关于同时开始盆底物理治疗(PFPT)和药物治疗膀胱过度活动症的文献有限。尽管依从性往往较低,但PFPT可改善患者症状。这项回顾性队列研究评估了在三级医疗中心被转诊至PFPT的膀胱过度活动症女性患者的PFPT依从性。我们假设,对于膀胱过度活动症患者,同时进行PFPT和药物治疗与PFPT依从性降低相关。
比较了接受(PT + 药物组)和未接受(PT组)同时药物处方的患者对PFPT的依从性(定义为参加推荐疗程的≥50%)。
我们评估了346例患者,其中PT组196例,PT + 药物组150例。PT + 药物组的体重指数更高(30.0 kg/m²对27.5 kg/m²,p < 0.001),糖尿病发生率更高(20.7%对11.7%,p = 0.02),且基线时泌尿生殖系统困扰量表评分更高(p < 0.001)。PT组完成的PT疗程更多(p < 0.001),且更有可能依从(30.6%对15.3%,p < 0.001)。PT + 药物组更有可能进展为微创治疗(10.0%对4.1%,p = 0.03)。在多变量逻辑回归模型中,在控制合并症时,PT + 药物组的PFPT依从性仍然显著较低(调整后的OR为0.38,p = 0.001)。
在转诊进行PFPT时加用药物与膀胱过度活动症患者PFPT依从性降低相关。