Madden Alexandra, Moser Melanie, Eisen Howard
Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Curr Cardiol Rep. 2025 Jul 22;27(1):117. doi: 10.1007/s11886-025-02267-y.
To identify potential preoperative risk factors that predispose a patient to developing a left ventricular assist device driveline infection.
The fully magnetically-levitated left ventricular assist device has proven to be a safe and effective durable option for patients with advanced heart failure. However, driveline infections are a significant adverse event that impact patient mortality, morbidity, and quality of life. Potential preoperative risk factors such as INTERMACS score, temporary cardiovascular support, body mass index, hemoglobin A1C, prealbumin, infection, and hospital length of stay do not appear to significantly predispose a patient to developing a left ventricular assist device driveline infection. There is a need for more extensive research on postoperative patient and driveline management in order to identify high risk patients and delineate best practice to decrease the risk and burden of driveline infections.
确定使患者易发生左心室辅助装置驱动线感染的潜在术前危险因素。
全磁悬浮左心室辅助装置已被证明是晚期心力衰竭患者安全有效的长期治疗选择。然而，驱动线感染是一种严重的不良事件，会影响患者的死亡率、发病率和生活质量。INTERMACS评分、临时心血管支持、体重指数、糖化血红蛋白、前白蛋白、感染和住院时间等潜在术前危险因素似乎并未显著使患者易发生左心室辅助装置驱动线感染。需要对术后患者和驱动线管理进行更广泛的研究，以识别高危患者并确定最佳实践，以降低驱动线感染的风险和负担。
