巴尔的摩黑人年轻及老年女性中暴露前预防(PrEP)使用的促进因素与障碍:一项定性研究
Facilitators and Barriers to Pre-Exposure Prophylaxis (PrEP) Use Among Black Young and Older Adult Women in Baltimore: A Qualitative Study.
作者信息
Knight Deja, Willie Tiara C, Baral Stefan, German Danielle, Saleem Haneefa
机构信息
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, 21205, MD, U.S.A..
Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, U.S.A.
出版信息
J Racial Ethn Health Disparities. 2025 Jul 22. doi: 10.1007/s40615-025-02549-9.
BACKGROUND
The majority of incident HIV infections among women in the US occur among Black cisgender women with significant heterogeneity by age. This study aimed to explore the differences in PrEP barriers and facilitators among Black young and older adult women in Baltimore, Maryland.
METHODS
We purposively recruited young adult 18 to 29 (n = 12) and older adult women ages 30 to 44 (n = 14) from Baltimore, Maryland, who have never used PrEP to participate in a semi-structured interview. We utilized a combination of deductive and inductive coding to analyze the data. Coded segments were analyzed by age group and were presented using the socioecological model.
FINDINGS
At the individual level, low PrEP awareness and knowledge, lack of perceived PrEP candidacy, and concerns about PrEP side effects and efficacy were barriers to PrEP interest. At the relationship level, monogamy and anticipated partner reaction to PrEP use (only for young adult Black women) were barriers to PrEP interest. At the community level, HIV stigma impeded PrEP interest, whereas sexual norms in college among young adult Black women contributed to PrEP interest. Finally, on a structural level, medical mistrust and PrEP costs were barriers to PrEP interest.
CONCLUSIONS
Taken together, these data suggest the need for increasingly tailored approaches to better serve young and older adult Black women. Engaging Black women in specific venues such as health centers on college campuses may be optimal to reach young adult Black women, whereas healthcare settings may be optimal to reach older adult Black women.
背景
美国女性中大多数新感染艾滋病毒的情况发生在黑人顺性别女性中,且按年龄存在显著差异。本研究旨在探讨马里兰州巴尔的摩市年轻和年长成年黑人女性在暴露前预防(PrEP)障碍及促进因素方面的差异。
方法
我们从马里兰州巴尔的摩市有目的地招募了18至29岁的年轻成年女性(n = 12)和30至44岁的年长成年女性(n = 14),她们从未使用过PrEP,并参与了一次半结构化访谈。我们采用演绎编码和归纳编码相结合的方法来分析数据。编码片段按年龄组进行分析,并使用社会生态模型呈现。
研究结果
在个体层面,PrEP意识和知识水平低、认为自己不适合使用PrEP、以及对PrEP副作用和疗效的担忧是影响PrEP兴趣的障碍。在关系层面,一夫一妻制以及预期伴侣对使用PrEP的反应(仅针对年轻成年黑人女性)是影响PrEP兴趣的障碍。在社区层面,艾滋病毒污名阻碍了PrEP兴趣,而年轻成年黑人女性在大学中的性规范则促进了PrEP兴趣。最后,在结构层面,对医疗的不信任和PrEP成本是影响PrEP兴趣的障碍。
结论
总体而言,这些数据表明需要采取越来越有针对性的方法,以更好地服务年轻和年长成年黑人女性。在大学校园健康中心等特定场所接触黑人女性可能最适合接触年轻成年黑人女性,而医疗保健场所可能最适合接触年长成年黑人女性。