Luff A, Nguyen N C, Luong T N, Hayford S, Norris A, Casterline J, Andridge R, Gallo M F
Division of Epidemiology, College of Public Health, Ohio State University.
Department of Obstetrics and Gynecology, Vinmec International Hospital.
J Sex Res. 2025 Jul 22:1-8. doi: 10.1080/00224499.2025.2530230.
We examined the association between negative pregnancy desires and women's semen exposure, a measure of recent condomless sex, among 500 different-sex couples using condoms for contraception. We analyzed data from a trial in Thanh Hoa, Vietnam which longitudinally assessed women's semen exposure via prostate-specific antigen in vaginal fluid. At enrollment, partners independently reported the importance of avoiding pregnancy for the next six months. Assessing negative pregnancy desires as strong-negative (very important) versus not strong-negative (important/neutral), we evaluated partner concordance of desires and compared this against semen exposure using log-binomial generalized estimating equations. While 59% of men and 58% of women reported strong-negative pregnancy desires, 45% of couples had partner-concordant strong-negative desires. Couples with partner-concordant strong-negative desires had reduced risk of semen exposure (aRR 0.58, 95% CI [0.34, 0.99]) compared to couples without strong-negative desires. Similarly, couples where only one partner had a strong-negative desire had lower semen exposure than couples without strong-negative desires (aRR 0.60, 95% CI [0.38, 0.95]). Couples were less likely to engage in condomless sex when either partner had strong desires to prevent pregnancy, regardless of the gender of the partner with strong-negative desires. This highlights the importance of considering both partners' desires in contraceptive counseling to prevent condomless sex and unintended pregnancy.
我们在500对使用避孕套避孕的异性伴侣中,研究了负面妊娠意愿与女性精液接触(一种衡量近期无保护性行为的指标)之间的关联。我们分析了越南清化省一项试验的数据,该试验通过检测阴道液中前列腺特异性抗原纵向评估女性的精液接触情况。在入组时,伴侣双方独立报告未来六个月内避免怀孕的重要性。将负面妊娠意愿评估为强烈负面(非常重要)与非强烈负面(重要/中性),我们评估了伴侣意愿的一致性,并使用对数二项式广义估计方程将其与精液接触情况进行比较。虽然59%的男性和58%的女性报告有强烈负面妊娠意愿,但45%的伴侣双方有一致的强烈负面意愿。与没有强烈负面意愿的伴侣相比,伴侣双方有一致强烈负面意愿的伴侣精液接触风险降低(调整风险比0.58,95%置信区间[0.34, 0.99])。同样,只有一方有强烈负面意愿的伴侣比没有强烈负面意愿的伴侣精液接触率更低(调整风险比0.60,95%置信区间[0.38, 0.95])。当任何一方有强烈的避孕意愿时,伴侣进行无保护性行为的可能性较小,无论有强烈负面意愿的伴侣性别如何。这突出了在避孕咨询中考虑双方意愿对于预防无保护性行为和意外怀孕的重要性。