Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States; Vanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, TN, United States.
Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Contraception. 2022 Aug;112:23-36. doi: 10.1016/j.contraception.2022.05.001. Epub 2022 May 14.
Systematically review the existing evidence about couples-based interventions and postpartum contraceptive uptake and generate recommendations for future research.
PubMed, Web of Science, PsycINFO, Embase, and CINAHL through June 7, 2021.
Studies with a couples-based intervention assessing postpartum contraceptive uptake. Two independent reviewers screened studies, extracted data, and assessed risk of bias with RoB-2 (Cochrane Risk of Bias 2) for randomized and ROBINS-I (Risk of Bias in Non-Randomized Studies - Interventions) for observational studies. Data were synthesized in tables, figures, and a narrative review.
A total of 925 papers were identified, 66 underwent full text review, and 17 articles, which included 18 studies - 16 randomized, 2 observational - were included. The lack of intervention and outcome homogeneity precluded meta-analysis and isolating the effect of partner involvement. Four studies were partner-required, where partner involvement was a required component of the intervention, and 14 were partner-optional. Unadjusted risk differences ranged from 0.01 to 0.51 in favor of couples-based interventions increasing postpartum contraceptive uptake versus standard of care. Bias assessment of the 16 randomized studies classified 8, 3, and 5 studies as at a high, some concern, and low risk of bias. Common sources of bias included intervention non-adherence and missing outcome data. One observational study was at a high and the other at a low risk of bias.
Future studies that assess couples-based interventions must clearly define and measure how partners are involved in the intervention and assess how intervention adherence impacts postpartum contraceptive uptake.
系统回顾现有的关于基于伴侣的干预措施与产后避孕措施使用率的证据,并为未来的研究提供建议。
PubMed、Web of Science、PsycINFO、Embase 和 CINAHL,检索时间截至 2021 年 6 月 7 日。
以基于伴侣的干预措施评估产后避孕措施使用率为研究对象。两名独立的审查员筛选研究,提取数据,并使用 RoB-2(Cochrane 风险偏倚 2)评估随机对照研究和 ROBINS-I(非随机对照研究干预措施偏倚风险)评估观察性研究的风险偏倚。数据以表格、图形和叙述性综述的形式进行综合。
共确定了 925 篇论文,其中 66 篇进行了全文审查,17 篇文章(包括 18 项研究)被纳入,其中 16 项为随机对照研究,2 项为观察性研究。由于干预措施和结局缺乏同质性,无法进行荟萃分析,也无法确定伴侣参与的影响。其中 4 项研究要求伴侣参与,即伴侣参与是干预措施的一个必要组成部分,而 14 项研究则为伴侣可选。未调整的风险差异从 0.01 到 0.51 不等,表明基于伴侣的干预措施与常规护理相比,增加了产后避孕措施的使用率。对 16 项随机对照研究的偏倚评估结果显示,其中 8 项、3 项和 5 项研究的偏倚风险分别为高、中度关注和低。常见的偏倚来源包括干预措施的不依从和结局数据缺失。其中 1 项观察性研究的偏倚风险为高,另 1 项为低。
未来评估基于伴侣的干预措施的研究必须明确界定和衡量伴侣如何参与干预措施,并评估干预措施的依从性如何影响产后避孕措施的使用率。