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乳腺脓肿手术治疗的临床结果及复发预测因素:一项回顾性分析

Clinical outcomes and recurrence predictors in breast abscess surgical management: A retrospective analysis.

作者信息

Dolu Fatih, Ay Oğuzhan Fatih, Küpeli Aydin Hakan

机构信息

Kahramanmaras Necip Fazil City Hospital, Surgical Oncology Clinic, Kahramanmaras, Turkey.

Kahramanmaras Necip Fazil City Hospital, General Surgery Clinic, Kahramanmaras, Turkey.

出版信息

Medicine (Baltimore). 2025 Jul 18;104(29):e43280. doi: 10.1097/MD.0000000000043280.

Abstract

Breast abscesses are common in surgical practice, with significant recurrence rates. Identifying factors associated with recurrence is crucial for guiding management and improving outcomes. This study aimed to evaluate the clinical, pathological, radiological, and laboratory factors associated with recurrence in patients who underwent surgical treatment for breast abscesses. This retrospective observational study included female patients who were managed surgically for breast abscesses between January 2018 and June 2024. The data included demographic, surgical, pathological, and laboratory parameters. Statistical analyses were performed to compare the recurrence and non-recurrence groups and identify significant predictors of recurrence. Logistic regression analysis was applied to determine independent predictors of recurrence. A total of 55 patients who underwent surgical treatment for breast abscesses were included in the study. Recurrence was observed in 30.9% of the patients (n = 17). In intergroup comparisons, lower hemoglobin levels were associated with recurrence (mean: 12.1 vs 13.09 g/dL; P = .057; mean difference: -0.994; 95% CI: -2.018 to 0.030), and recurrence was more frequent among Syrian-immigrant patients (17.6% vs 2.6%; χ2 = 3.927; P = .048). Logistic regression identified granulomatous mastitis as a significant predictor, increasing the risk of recurrence (OR: 62.7; 95% CI: 1.98-1981.4; P = .031). This study highlights the high recurrence rate of surgically treated breast abscesses and the heterogeneity of the condition, which includes diverse etiologies. Preoperative patient counseling regarding recurrence risk is essential to strengthen the patient-physician relationship.

摘要

乳腺脓肿在外科临床实践中很常见,复发率较高。识别与复发相关的因素对于指导治疗和改善治疗效果至关重要。本研究旨在评估接受乳腺脓肿手术治疗患者复发相关的临床、病理、放射学和实验室因素。这项回顾性观察性研究纳入了2018年1月至2024年6月期间接受乳腺脓肿手术治疗的女性患者。数据包括人口统计学、手术、病理和实验室参数。进行统计分析以比较复发组和非复发组,并确定复发的显著预测因素。应用逻辑回归分析来确定复发的独立预测因素。共有55例接受乳腺脓肿手术治疗的患者纳入本研究。30.9%的患者(n = 17)出现复发。组间比较中,较低的血红蛋白水平与复发相关(平均值:12.1 vs 13.09 g/dL;P = 0.057;平均差异:-0.994;95% CI:-2.018至0.030),叙利亚移民患者复发更频繁(17.6% vs 2.6%;χ2 = 3.927;P = 0.048)。逻辑回归确定肉芽肿性乳腺炎是一个显著的预测因素,增加了复发风险(OR:62.7;95% CI:1.98 - 1981.4;P = 0.031)。本研究强调了手术治疗乳腺脓肿的高复发率以及该疾病的异质性,包括多种病因。术前就复发风险对患者进行咨询对于加强医患关系至关重要。

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本文引用的文献

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Idiopathic Granulomatous Mastitis.特发性肉芽肿性乳腺炎。
Breast J. 2024 Jan 25;2024:6693720. doi: 10.1155/2024/6693720. eCollection 2024.
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Breast Infection: A Review of Diagnosis and Management Practices.乳腺感染:诊断与管理实践综述
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