Xingyan Fang, Xingkun Ou, Yonglin Hu, Xiao Daimin
Department of Clinical Laboratory, Kweichow Moutai Hospital, Zunyi 564500, China.
Department of Clinical Laboratory, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563100, China.
IDCases. 2025 Jul 9;41:e02318. doi: 10.1016/j.idcr.2025.e02318. eCollection 2025.
infections are exceptionally rare and frequently necessitate sophisticated laboratory analyses for precise identification. In this report, we detail a case of bacteremia in a patient suffering from adrenoleukodystrophy, a rare hereditary metabolic disorder. The diagnosis was validated using 16S rRNA gene sequencing, emphasizing the pivotal role of advanced molecular methodologies in pinpointing uncommon pathogens.Vancomycin was the preferred antibiotic for the treatment of infection. This case accentuates the importance of considering rare pathogens, particularly in patients with intricate medical backgrounds.
感染极为罕见，通常需要进行复杂的实验室分析才能准确识别。在本报告中，我们详细介绍了一例患有肾上腺脑白质营养不良（一种罕见的遗传性代谢紊乱疾病）患者的菌血症病例。通过16S rRNA基因测序验证了诊断结果，强调了先进分子方法在查明罕见病原体方面的关键作用。万古霉素是治疗该感染的首选抗生素。该病例凸显了考虑罕见病原体的重要性，尤其是在具有复杂病史的患者中。
