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经F-FAPI PET/CT检测腹股沟区种植转移的胃癌:一例报告

Detection of gastric cancer with implantation metastasis to the inguinal region via F-FAPI PET/CT: a case report.

作者信息

Zhang Haibo, Hao Shanhu, Wu Tong, Wu Zhongbao, Liu Xuantong, Xu Ying, Zhang Peng, Yan Ying

机构信息

Department of Radiation Oncology, General Hospital of Northern Theater Command, Shenyang, Liaoning, China.

Department of Nuclear Medicine, General Hospital of Northern Theater Command, Shenyang, Liaoning, China.

出版信息

Front Oncol. 2025 Jul 8;15:1549825. doi: 10.3389/fonc.2025.1549825. eCollection 2025.

Abstract

Implantation metastasis of gastric cancer to the inguinal area is rarely reported, and a clear diagnosis of such metastasis is hard to make, especially when these cancers are invisible on fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging. However, certain types of cancers, such as signet-ring cell carcinoma, are particularly sensitive to fibroblast activation protein inhibitor (FAPI) PET/CT. In this case, a patient with a history of gastric cancer and a gastrectomy 2 years previously suddenly developed serious edema in his right lower limb. With the help of FAPI PET/CT and other laboratory findings, abdominal implantation of his primary gastric cancer to the inguinal region was confirmed. After prompt treatment, the patient had a favorable prognosis.

摘要

胃癌向腹股沟区的种植转移鲜有报道,且此类转移的明确诊断很难做出,尤其是当这些癌症在氟脱氧葡萄糖(FDG)正电子发射断层扫描/计算机断层扫描(PET/CT)成像上不可见时。然而,某些类型的癌症,如印戒细胞癌,对成纤维细胞活化蛋白抑制剂(FAPI)PET/CT特别敏感。在本病例中,一名有胃癌病史且两年前接受过胃切除术的患者右下肢突然出现严重水肿。借助FAPI PET/CT及其他实验室检查结果,证实其原发性胃癌向腹股沟区发生了腹腔种植转移。经过及时治疗,患者预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a55/12279501/03440a3d1e69/fonc-15-1549825-g001.jpg

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