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前交叉韧带损伤手术治疗的临床及社会预测因素

Clinical and Social Predictors of Surgical Treatment for Anterior Cruciate Ligament Injuries.

作者信息

Ginjupalli Rithika, Orav Endel J, McCleary Nadine J, Hubbell Harrison T, Tanaka Miho J

机构信息

University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

出版信息

Orthop J Sports Med. 2025 Jul 21;13(7):23259671251336395. doi: 10.1177/23259671251336395. eCollection 2025 Jul.

Abstract

BACKGROUND

While anterior cruciate ligament (ACL) injury is often managed surgically in the young, active population, nonoperative management may be considered in older adults. Surgical decision-making in adults is usually based on patient preference, level of functional disability, and the presence of comorbidities. Understanding the role of clinical predictors in surgical decision-making can help identify disparities in treatment outcomes.

PURPOSE

To report on clinical and social predictors of surgical versus nonsurgical treatment in patients with ACL injuries and quantify the influence of each factor.

STUDY DESIGN

Case control study; Level of evidence, 3.

METHODS

Patients diagnosed with ACL injury and those who underwent subsequent ACL reconstruction at a single center were identified. Functional disability was determined using patient-reported outcome measure scores, including the Knee injury and Osteoarthritis Outcome Score Physical Function Short Form (KOOS-PS) and Patient-Reported Outcomes Measurement Information Systems Physical Function (PROMIS-PF) within 90 days of diagnosis and before surgery. Clinical and sociodemographic factors were collected, and comorbidities were recorded using the Charlson Comorbidity Index. Logistic regression analysis was performed to identify relationships between clinical and sociodemographic factors with the likelihood of undergoing surgery for their ACL injury.

RESULTS

A total of 3656 patients were identified with ACL tear; 1734 (47.4%) were female (mean age, 34.9 years; SD, 13.8 years) and 1922 (52.6%) were male (mean age, 32.8 years; SD, 13.1 years). Overall, 53.8% of female patients and 53.4% of male patients underwent surgical treatment. Women had lower KOOS-PS and PROMIS values compared with men (-4.1 [ < .001] and -2.0 [ < .001], respectively) at the time of initial evaluation. Older age ( < .001), greater body mass index ( = .014), greater comorbidities ( < .001), smoking ( = .06), and subsidized insurance ( < .001) were negative predictors of surgery.

CONCLUSION

Older age, greater body mass index, greater comorbidities, smoking, and subsidized insurance were negative predictors of undergoing surgical management of ACL injuries. Clinical predictors are useful in highlighting disparities and understanding ACL reconstruction decision-making for patients.

摘要

背景

虽然前交叉韧带(ACL)损伤在年轻活跃人群中通常采用手术治疗,但老年患者可考虑非手术治疗。成人的手术决策通常基于患者偏好、功能残疾程度和合并症情况。了解临床预测因素在手术决策中的作用有助于识别治疗结果的差异。

目的

报告ACL损伤患者手术与非手术治疗的临床和社会预测因素,并量化各因素的影响。

研究设计

病例对照研究;证据等级为3级。

方法

确定在单一中心诊断为ACL损伤并随后接受ACL重建的患者。在诊断后90天内且手术前,使用患者报告的结局测量评分来确定功能残疾情况,包括膝关节损伤和骨关节炎结局评分身体功能简表(KOOS-PS)和患者报告结局测量信息系统身体功能(PROMIS-PF)。收集临床和社会人口学因素,并使用Charlson合并症指数记录合并症情况。进行逻辑回归分析,以确定临床和社会人口学因素与因ACL损伤接受手术可能性之间的关系。

结果

共识别出3656例ACL撕裂患者;其中1734例(47.4%)为女性(平均年龄34.9岁;标准差13.8岁),1922例(52.6%)为男性(平均年龄32.8岁;标准差13.1岁)。总体而言,53.8%的女性患者和53.4%的男性患者接受了手术治疗。在初次评估时,女性的KOOS-PS和PROMIS值低于男性(分别为-4.1[<.001]和-2.0[<.001])。年龄较大(<.001)、体重指数较高(=.014)、合并症较多(<.001)、吸烟(=.06)和有补贴保险(<.001)是手术的负性预测因素。

结论

年龄较大、体重指数较高、合并症较多、吸烟和有补贴保险是ACL损伤接受手术治疗的负性预测因素。临床预测因素有助于突出差异并理解患者的ACL重建决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d576/12280533/c42d4bc40460/10.1177_23259671251336395-fig1.jpg

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