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adeno-associated virus-mediated LDLR/PCSK9 intervention for familial hypercholesterolemia.

作者信息

Han Zeyu, Tan Cheng, Ai Jianzhong, Zhu Ye

机构信息

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.

Department of Cardiology, Institute of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.

出版信息

Genes Dis. 2025 Apr 10;12(6):101632. doi: 10.1016/j.gendis.2025.101632. eCollection 2025 Nov.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9072/12281168/f6f25d41de74/gr1.jpg

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本文引用的文献

1
Genetic and molecular architecture of familial hypercholesterolemia.
J Intern Med. 2023 Feb;293(2):144-165. doi: 10.1111/joim.13577. Epub 2022 Oct 17.
2
Familial Hypercholesterolemia: JACC Focus Seminar 4/4.
J Am Coll Cardiol. 2021 Nov 2;78(18):1831-1843. doi: 10.1016/j.jacc.2021.09.004.
3
Nutritional and Lipid Modulation of PCSK9: Effects on Cardiometabolic Risk Factors.
J Nutr. 2017 Apr;147(4):473-481. doi: 10.3945/jn.116.235069. Epub 2017 Feb 8.
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Further LDL cholesterol lowering through targeting PCSK9 for coronary artery disease.
Endocr Metab Immune Disord Drug Targets. 2008 Dec;8(4):238-43. doi: 10.2174/187153008786848286.
5

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