Smith B T, Torday J S
Pediatr Pulmonol. 1985 May-Jun;1(3 Suppl):S49-52.
Although there is much yet to be learned about the regulation of fetal lung maturation, the study of this process has yielded much information that may serve as a paradigm for the understanding of fetal growth regulation in general. Two particularly interesting fetal adjustments of general regulatory phenomena have emerged: the ability of local tissue metabolism to anatomically or temporally isolate endocrine effects and the role of paracrine factors in coordinating the responses of different cells in complex organs.
尽管关于胎儿肺成熟的调节仍有许多有待了解之处,但对这一过程的研究已产生了许多信息,这些信息可能成为理解一般胎儿生长调节的范例。已经出现了两种特别有趣的一般调节现象的胎儿适应性变化:局部组织代谢在解剖学或时间上隔离内分泌作用的能力,以及旁分泌因子在协调复杂器官中不同细胞反应方面的作用。