Nishiguchi Sho, Sugaya Nagisa, Akiyama Miyo, Inamori Masahiko
Department of Public Health Yokohama City University Yokohama Japan.
Department of General Internal Medicine Shonan Kamakura General Hospital Kamakura Japan.
Health Sci Rep. 2025 Jul 21;8(7):e70944. doi: 10.1002/hsr2.70944. eCollection 2025 Jul.
This study examined to identify predictive factors for oral intake recovery in patients with acute illness after discharge from an acute care hospital.
The prospective cohort study was conducted at an acute care hospital between January and December 2020. Among 3359 consecutive patients who required speech therapy rehabilitation after acute illness treatment, those with oral intake difficulty were selected. After discharge, patients were followed up at home care service, long-term care facility, or sub-acute hospital. Difficulty in oral intake was defined based on the dysphagia grade by speech-language pathologists and overall oral intake consumption. The primary outcome measure was the recovery of total oral intake 90 days after discharge. We analyzed the clinically relevant factors for oral intake recovery using a multivariate logistic regression model.
Among 512 patients with severe dysphagia and insufficient oral intake upon discharge, 410 were ultimately included (response rate: 80.0%) from 106 facilities, comprising a home care service, a long-term care facility, and another hospital. The mean age was 83.2 years, with 52.9% of the patients being men. The median length of the hospital stay was 27 days. Overall, 195 (47.4%) patients survived, and 57 (13.9%) recovered their oral intake 90 days after discharge. In the multivariable analysis, the absence of nocturnal suctioning (adjusted odds ratio = 3.8, 95% confidence interval: 1.9-7.5, < 0.001), communication ability ( = 0.021), and artificial hydration and nutrition ( = 0.001) were significant factors associated with oral intake recovery within 90 days after discharge.
The factors identified in this study may contribute to prognosis of patients who can recover their oral intake at discharge from acute care hospitals and to the implementation of appropriate discharge plans and artificial hydration and nutrition.
本研究旨在确定急性病患者从急症医院出院后经口摄入恢复的预测因素。
前瞻性队列研究于2020年1月至12月在一家急症医院进行。在3359例急性病治疗后需要言语治疗康复的连续患者中,选取存在经口摄入困难的患者。出院后,在家庭护理服务机构、长期护理机构或亚急性医院对患者进行随访。经口摄入困难根据言语病理学家的吞咽困难分级和总体经口摄入量来定义。主要结局指标是出院90天后经口摄入总量的恢复情况。我们使用多变量逻辑回归模型分析经口摄入恢复的临床相关因素。
在512例出院时存在严重吞咽困难且经口摄入量不足的患者中,最终纳入了来自106个机构(包括家庭护理服务机构、长期护理机构和另一家医院)的410例患者(应答率:80.0%)。平均年龄为83.2岁,52.9%的患者为男性。住院中位时长为27天。总体而言,195例(47.4%)患者存活,57例(13.9%)患者在出院90天后恢复了经口摄入。在多变量分析中,夜间无吸痰(调整后的优势比 = 3.8,95%置信区间:1.9 - 7.5,< 0.001)、沟通能力( = 0.021)以及人工补液和营养( = 0.001)是与出院后90天内经口摄入恢复相关的显著因素。
本研究确定的因素可能有助于预测急性病医院出院患者经口摄入恢复的预后,并有助于实施适当的出院计划以及人工补液和营养措施。