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一名65岁耐力运动员严重主动脉缩窄的延迟诊断:对运动生理学和侧支循环代偿的见解

Late diagnosis of severe aortic coarctation in a 65-year-old endurance athlete: Insights into exercise physiology and collateral compensation.

作者信息

Sharma Arundhati, Sharma Anubhuti, Chaliki Kalyan, Fernandes Marco Antonio, Marcotte Francois, Reddy Satyajit

机构信息

Mayo Clinic, 13400 E, Shea Blvd, Scottsdale, AZ, 85259, USA.

The University of Arizona College of Medicine - Phoenix, 475 N 5th St, Phoenix, AZ, 85004, USA.

出版信息

Int J Cardiol Congenit Heart Dis. 2025 Jun 30;21:100606. doi: 10.1016/j.ijcchd.2025.100606. eCollection 2025 Sep.

Abstract

BACKGROUND

Coarctation of the aorta (CoA) is a relatively rare congenital narrowing of the distal aortic arch to proximal descending thoracic aorta, usually diagnosed in infancy or early childhood with upper extremity hypertension as a typical finding. Late detection in asymptomatic, physically active older adults is rare and can be clinically significant.

CASE PRESENTATION

We present the case of a 65-year-old lifelong endurance athlete found to have transient severe left ventricular (LV) systolic dysfunction after completing a marathon. Stress testing revealed a hypertensive response, prompting cardiac MRI, which detected a new severe juxta-ductal CoA with collateralization. The patient underwent successful endovascular stenting with improved blood pressure response and stabilization of LV function.

CONCLUSION

This case underscores the importance of thorough cardiovascular assessment in older athletes and highlights the impact of lifelong exercise in compensating for congenital defects like CoA.

摘要

背景

主动脉缩窄(CoA)是一种相对罕见的先天性疾病,表现为主动脉弓远端至胸降主动脉近端的狭窄,通常在婴儿期或幼儿期被诊断出来,典型症状是上肢高血压。在无症状、身体活跃的老年人中晚期才被发现的情况很少见,但具有临床意义。

病例介绍

我们报告了一名65岁的终身耐力运动员的病例,该运动员在完成马拉松比赛后被发现出现短暂性严重左心室(LV)收缩功能障碍。压力测试显示有高血压反应,促使进行心脏磁共振成像(MRI)检查,结果发现了一处新的严重导管旁主动脉缩窄并伴有侧支循环。该患者接受了成功的血管内支架置入术,血压反应改善,左心室功能稳定。

结论

本病例强调了对老年运动员进行全面心血管评估的重要性,并突出了终身运动在补偿诸如主动脉缩窄等先天性缺陷方面的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12281131/1984e8a9e417/gr1.jpg

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