Walther F J, Wu P Y, Siassi B
Pediatrics. 1985 Dec;76(6):918-21.
Phototherapy is known to increase peripheral blood flow in neonates, but information on the associated cardiovascular effects is not available. Using pulsed Doppler echocardiography we evaluated cardiac output and stroke volume in 12 preterm and 13 term neonates during and after phototherapy. We concomitantly measured arterial limb blood flow by strain gauge plethysmography and skin blood flow by photoplethysmography. Cardiac output decreased by 6% due to reduced stroke volume during phototherapy, whereas total limb blood flow and skin blood flow increased by 38% and 41%, respectively. Peripheral blood flow increments tended to be higher in the preterm than in the term infants. The reduced stroke volume during phototherapy may be an expression of reduced activity of the newborn during phototherapy. For healthy neonates the reduction in cardiac output is minimal, but for sick infants with reduced cardiac output, this reduction may further aggravate the decrease in tissue perfusion.
众所周知，光疗可增加新生儿的外周血流量，但关于其相关心血管效应的信息尚不可得。我们使用脉冲多普勒超声心动图评估了12例早产儿和13例足月儿在光疗期间及光疗后的心输出量和每搏输出量。我们同时通过应变片体积描记法测量肢体动脉血流量，并通过光电容积描记法测量皮肤血流量。由于光疗期间每搏输出量减少，心输出量下降了6%，而肢体总血流量和皮肤血流量分别增加了38%和41%。早产儿的外周血流量增加趋势往往高于足月儿。光疗期间每搏输出量减少可能是新生儿在光疗期间活动减少的一种表现。对于健康新生儿，心输出量的减少是最小的，但对于心输出量降低的患病婴儿，这种减少可能会进一步加重组织灌注的下降。
