Steele R W, McConnell J R, Jacobs R F, Mawk J R
Pediatrics. 1985 Dec;76(6):950-3.
Three patients with histories of recurrent bacterial meningitis were previously examined with skull and sinus radiographs, routine cranial computed tomography, intrathecal radioisotope tracer studies, and immunologic evaluation. None of these studies were diagnostic. Pneumococcal vaccine and prophylactic penicillin therapy were ineffective in preventing recurrent episodes in two cases. Thin-section (2-mm) direct coronal computed cranial tomography demonstrated anatomic defects in all three patients. The use of metrizamide cisternography was not necessary to diagnose the defects. All patients had basiethmoidal encephaloceles which were repaired surgically. Direct coronal computed tomography offers a relatively easy noninvasive method for delineating anatomic abnormalities in patients with recurrent meningitis.
三名有复发性细菌性脑膜炎病史的患者此前接受了头颅和鼻窦X光片、常规头颅计算机断层扫描、鞘内放射性同位素示踪剂研究以及免疫学评估。这些检查均未得出诊断结果。肺炎球菌疫苗和预防性青霉素治疗对其中两例预防复发无效。薄层(2毫米)直接冠状位头颅计算机断层扫描显示所有三名患者均存在解剖学缺陷。诊断这些缺陷无需使用甲泛葡胺脑池造影。所有患者均患有筛骨底部脑膨出,并接受了手术修复。直接冠状位计算机断层扫描为描绘复发性脑膜炎患者的解剖学异常提供了一种相对简便的非侵入性方法。