埃勒斯-当洛综合征患者的睡眠特征

Sleep Characteristics in Individuals with Ehlers-Danlos Syndrome.

作者信息

Crews-Stowe Caitlin, Tudini Frank, Jung Min-Kyung, Forman Jake, Riley Bernadette, Eton Stephanie, Levine David

机构信息

Health and Human Performance Department, University of Tennessee at Chattanooga, Chattanooga, TN 37403, USA.

Physical Therapy Department, University of Tennessee at Chattanooga, Chattanooga, TN 37403, USA.

出版信息

Med Sci (Basel). 2025 Jun 27;13(3):85. doi: 10.3390/medsci13030085.

Abstract

The presence of Ehlers-Danlos Syndromes (EDSs) has significant effects on overall health and results in varying levels of pain and disability. The effects of sleep are not well documented in this population. The purpose of this study is to report the sleep characteristics of people with EDS. An electronic survey regarding sleep characteristics was created and distributed through the EDS website. Sleep disturbance is common in people with EDS, with 65.3% of respondents sleeping fewer than 8 h and 26.2% averaging fewer than 6 h. Those who slept fewer than 6 h reported more days of poor mental and physical health days. Sleep aids were commonly used with 41.40% of patients regularly taking prescription medication to get to sleep. Sleep latency of greater than 30 min was also found in 67.5% of subjects. The results demonstrate an association between people with EDS and poorer sleep duration, increased sleep latency, and increased use of sleep aids including prescription sleep medication compared to the general population. While more research needs to be completed in this area, sleep may be an important aspect to address in the management of EDS.

摘要

埃勒斯-当洛综合征(EDS)的存在对整体健康有重大影响,并导致不同程度的疼痛和残疾。该人群中睡眠方面的影响尚无充分记录。本研究的目的是报告EDS患者的睡眠特征。一项关于睡眠特征的电子调查问卷被创建,并通过EDS网站进行分发。睡眠障碍在EDS患者中很常见,65.3%的受访者睡眠时间少于8小时,26.2%的受访者平均睡眠时间少于6小时。睡眠时间少于6小时的人报告称身心健康不佳的天数更多。睡眠辅助药物被广泛使用,41.40%的患者经常服用处方药来帮助入睡。67.5%的受试者还存在入睡潜伏期超过30分钟的情况。结果表明,与普通人群相比,EDS患者存在睡眠时间较短、入睡潜伏期延长以及包括处方睡眠药物在内的睡眠辅助药物使用增加的情况。虽然该领域还需要完成更多研究,但睡眠可能是EDS管理中需要解决的一个重要方面。

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