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经皮随机脉冲射频治疗脊柱疼痛病症:病例系列

A Transcutaneous Randomized Pulsed Radiofrequency Application for Spine Pain Conditions: A Case Series.

作者信息

Jorge Daniel de Moraes Ferreira, Rohof Olav, Jorge Melina Brigato Ferreira, Teixeira Alexandre, de Oliveira Cezar Augusto, Sobreiro Pablo, Dos Santos Douglas Freitas, Huber Stephany Cares, Lana Jose Fabio Santos Duarte

机构信息

Instituto Regenem de Medicina Avançada, São Paulo 04532-002, SP, Brazil.

Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil.

出版信息

J Funct Morphol Kinesiol. 2025 Jun 25;10(3):242. doi: 10.3390/jfmk10030242.

DOI:10.3390/jfmk10030242
PMID:40700178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12286087/
Abstract

Transcutaneous Randomized Pulsed Radiofrequency (TCPRF-STP) is a non-invasive therapeutic approach increasingly explored for managing spine-related pain, particularly in cases involving disc herniations and degenerative spine conditions. To evaluate the use of transcutaneous PRF-STP in the treatment of spine pathologies and its evolution in short-term follow-up. This case series examines the outcomes of three patients treated with TCPRF-STP for varying spine pathologies, including lumbar and cervical disc herniations, lumbar stenosis, and radiculopathy. All patients had previously undergone conventional conservative therapies without a satisfactory improvement and were unwilling or unable to undergo invasive procedures. The treatment involved the application of electromagnetic fields through adhesive skin patches at targeted sites. Patients underwent three sessions of TCPRF-STP, with follow-up assessments evaluating pain and MRI. Transcutaneous PRF-STP showed notable reductions in pain (VAS 0 in most cases), improvements in movement, and the restoration of normal daily activities. Follow-up MRI scans demonstrated positive structural changes in the treated discs. Although long-term recurrence occurred in one case, the patient remained active without functional limitations. Transcutaneous PRF-STP offers a promising, minimally invasive alternative for patients seeking to avoid surgery, though further studies with larger cohorts and longer follow-up periods are necessary to establish more robust evidence of its efficacy. This technique could become an important adjunct in managing chronic spinal pain conditions, offering patients an option with minimal risk and hospital demands.

摘要

经皮随机脉冲射频(TCPRF-STP)是一种用于治疗脊柱相关疼痛的非侵入性治疗方法,越来越多地被用于治疗椎间盘突出症和脊柱退行性疾病等病例。为了评估经皮PRF-STP在脊柱疾病治疗中的应用及其短期随访中的变化。本病例系列研究了三名接受TCPRF-STP治疗的不同脊柱疾病患者的治疗结果,包括腰椎和颈椎间盘突出症、腰椎管狭窄症和神经根病。所有患者此前均接受过传统保守治疗,但效果不佳,且不愿意或无法接受侵入性手术。治疗包括通过粘贴在皮肤上的贴片在目标部位施加电磁场。患者接受了三次TCPRF-STP治疗,并通过随访评估疼痛情况和进行MRI检查。经皮PRF-STP显示疼痛显著减轻(大多数情况下视觉模拟评分法为0)、活动能力改善以及日常活动恢复正常。随访MRI扫描显示治疗后的椎间盘有积极的结构变化。虽然有一例出现了长期复发,但该患者仍能正常活动,没有功能受限。经皮PRF-STP为寻求避免手术的患者提供了一种有前景的、微创的替代方法,不过需要进行更大样本量和更长随访期的进一步研究,以建立更有力的疗效证据。该技术可能成为管理慢性脊柱疼痛疾病的重要辅助手段,为患者提供风险最小且对医院要求最低的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ecf/12286087/24b396eed437/jfmk-10-00242-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ecf/12286087/413dc8dd4e8f/jfmk-10-00242-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ecf/12286087/28aa32ac5a70/jfmk-10-00242-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ecf/12286087/d2fb9665d791/jfmk-10-00242-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ecf/12286087/24b396eed437/jfmk-10-00242-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ecf/12286087/413dc8dd4e8f/jfmk-10-00242-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ecf/12286087/28aa32ac5a70/jfmk-10-00242-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ecf/12286087/d2fb9665d791/jfmk-10-00242-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ecf/12286087/24b396eed437/jfmk-10-00242-g004.jpg

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本文引用的文献

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Life (Basel). 2024 Dec 30;15(1):33. doi: 10.3390/life15010033.
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Transcutaneous electrical nerve stimulation for the treatment of acute postoperative pain following spine surgery: a scoping review.经皮神经电刺激治疗脊柱手术后急性术后疼痛:范围综述。
J Neurosurg Spine. 2024 Apr 12;41(1):97-104. doi: 10.3171/2024.1.SPINE231079. Print 2024 Jul 1.
3
The Anti-Inflammatory Action of Pulsed Radiofrequency-A Hypothesis and Potential Applications.
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Med Sci (Basel). 2023 Sep 10;11(3):58. doi: 10.3390/medsci11030058.
4
The Mechanism of Action between Pulsed Radiofrequency and Orthobiologics: Is There a Synergistic Effect?脉冲射频与骨生物制剂作用机制:是否存在协同效应?
Int J Mol Sci. 2022 Oct 3;23(19):11726. doi: 10.3390/ijms231911726.
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Study on the process of intervertebral disc disease by the theory of continuum damage mechanics.应用连续介质损伤力学理论研究椎间盘疾病的过程。
Clin Biomech (Bristol). 2022 Aug;98:105738. doi: 10.1016/j.clinbiomech.2022.105738. Epub 2022 Aug 12.
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Pulsed Radiofrequency in Interventional Pain Management: Cellular and Molecular Mechanisms of Action - An Update and Review.脉冲射频在介入性疼痛管理中的应用:作用的细胞和分子机制——更新与综述。
Pain Physician. 2021 Dec;24(8):525-532.
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