一名8岁男孩因抗癫痫治疗导致中毒性表皮坏死松解症。

Toxic epidermal necrolysis due to antiepileptic therapy in an 8-year-old boy.

作者信息

Muhar U, Granditsch G, Diem E

出版信息

Pediatr Dermatol. 1985 Nov;3(1):54-8. doi: 10.1111/j.1525-1470.1985.tb00487.x.

DOI:10.1111/j.1525-1470.1985.tb00487.x

Abstract

Toxic epidermal necrolysis (TEN) has rarely been documented in children. We treated an 8-year-old boy who developed generalized blistering dermatosis after anticonvulsive therapy with diphenylhydantoin. The diagnosis was proved by exfoliative cytology, histology, and electron microscopy. The disease entity and its differentiation from staphylococcal scalded-skin syndrome and toxic shock syndrome are reviewed.

摘要

中毒性表皮坏死松解症（TEN）在儿童中鲜有报道。我们治疗了一名8岁男孩，他在接受苯妥英抗惊厥治疗后出现了全身性水疱性皮肤病。通过脱落细胞学、组织学和电子显微镜检查证实了诊断。本文对该疾病实体及其与葡萄球菌烫伤样皮肤综合征和中毒性休克综合征的鉴别进行了综述。