Steinberg Adam G, Toussaint Nigel D, Davies Christopher E, Gray Nicholas A, McDonald Stephen P
Department of Nephrology, The Royal Melbourne Hospital, Parkville, Australia.
Department of Medicine (RMH), University of Melbourne, Parkville, Australia.
Nephrology (Carlton). 2025 Jul;30(7):e70076. doi: 10.1111/nep.70076.
The Australian and New Zealand Society of Nephrology (ANZSN) established a quality indicator (QI) program to measure performance and reduce variation of nephrology care. This program relies on registry data from the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA). ANZDATA also conducts surveys to ascertain more granular characteristics of participating nephrology units to better understand variation in practice. This study assessed ANZDATA and nephrology unit surveys to determine patient- and centre-level factors that may account for variation in dialysis access QIs.
Dialysis access QIs were evaluated over a 5-year period using ANZDATA (2016-2020). Patient characteristics were derived from the same period and dataset. Centre characteristics were determined from the 2020-unit binational survey. Statistical analysis involved multivariable regression with fixed effects for patient- and centre-characteristics and a random effect by centre.
Wide variation was seen across dialysis access QIs. Using multivariable regression, patient-level characteristics associated with definitive dialysis access at commencement of dialysis included male gender and body mass index decreasing from 30 kg/m. Centres with a home haemodialysis nurse and a 'peritoneal dialysis (PD) first policy' were associated with higher rates of definitive dialysis access. There was also a progressive relationship with the number of full-time equivalent (FTE) medical staff if the unit already had an FTE greater than 10. Inclusion of centre-level variables reduced the variance in the model by 68%.
This study demonstrates certain patient- and centre-level characteristics are associated with definitive dialysis access at the commencement of dialysis in Australia and New Zealand. Interventional trials for PD first programmes and different models of care for vascular access are needed.
澳大利亚和新西兰肾脏病学会(ANZSN)设立了一项质量指标(QI)计划,以衡量肾脏病护理的绩效并减少差异。该计划依赖于澳大利亚和新西兰透析与移植登记处(ANZDATA)的登记数据。ANZDATA还进行调查,以确定参与的肾脏病单位更详细的特征,以便更好地了解实践中的差异。本研究评估了ANZDATA和肾脏病单位调查,以确定可能导致透析通路质量指标差异的患者和中心层面的因素。
使用ANZDATA(2016 - 2020年)对5年期间的透析通路质量指标进行评估。患者特征来自同一时期和数据集。中心特征由2020年的双边单位调查确定。统计分析包括对患者和中心特征进行固定效应的多变量回归以及按中心进行随机效应分析。
透析通路质量指标存在广泛差异。通过多变量回归分析,透析开始时与确定性透析通路相关的患者层面特征包括男性性别以及体重指数从30kg/m²下降。拥有家庭血液透析护士和“优先采用腹膜透析(PD)政策”的中心与更高的确定性透析通路率相关。如果单位已经有超过10个全职等效(FTE)医务人员,那么与FTE医务人员数量也存在渐进关系。纳入中心层面变量使模型中的方差减少了68%。
本研究表明,在澳大利亚和新西兰,某些患者和中心层面的特征与透析开始时的确定性透析通路相关。需要针对优先采用PD方案和不同血管通路护理模式进行干预试验。