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Correction: A novel approach for highly sensitive and rapid identification of HMGA2 submicroscopic deletions in myeloproliferative neoplasms.更正:一种用于高灵敏度和快速鉴定骨髓增殖性肿瘤中HMGA2亚显微缺失的新方法。
Leukemia. 2025 Sep;39(9):2308. doi: 10.1038/s41375-025-02716-1.
2
A novel approach for highly sensitive and rapid identification of HMGA2 submicroscopic deletions in myeloproliferative neoplasms.一种用于高度敏感且快速鉴定骨髓增殖性肿瘤中HMGA2亚显微缺失的新方法。
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[The role of HMGA2 in myeloproliferative neoplasms].[HMGA2在骨髓增殖性肿瘤中的作用]
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Identification of a HMGA2-EFCAB6 gene rearrangement following next-generation sequencing in a patient with a t(12;22)(q14.3;q13.2) and JAK2V617F-positive myeloproliferative neoplasm.在一名患有t(12;22)(q14.3;q13.2)和JAK2 V617F阳性骨髓增殖性肿瘤的患者中,通过二代测序鉴定出HMGA2-EFCAB6基因重排。
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HMGA2 overexpression with specific chromosomal abnormalities predominate in CALR and ASXL1 mutated myelofibrosis.在伴有CALR和ASXL1突变的骨髓纤维化中,高迁移率族蛋白A2(HMGA2)过表达并伴有特定染色体异常的情况占主导。
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3'UTR-truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growth advantage at the level of HSC in mice.3'UTR 截短的 Hmga2 cDNA 通过在 HSC 水平赋予克隆生长优势导致类似于 MPN 的造血。
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Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferative neoplasms.骨髓增殖性肿瘤中 MIRLET7/HMGA2 轴的失调与 CDKN2A 启动子的甲基化有关。
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Interpretation of submicroscopic deletions of the BCR or ABL gene should not depend on extra signal-FISH: problems in interpretation of submicroscopic deletion of the BCR or ABL gene with extra signal-FISH.BCR或ABL基因亚显微缺失的解读不应依赖于额外信号荧光原位杂交:应用额外信号荧光原位杂交解读BCR或ABL基因亚显微缺失时存在的问题。
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Hmga2 collaborates with V617F in the development of myeloproliferative neoplasms.Hmga2与V617F在骨髓增殖性肿瘤的发展过程中相互协作。
Blood Adv. 2017 Jun 14;1(15):1001-1015. doi: 10.1182/bloodadvances.2017004457. eCollection 2017 Jun 27.

Correction: A novel approach for highly sensitive and rapid identification of HMGA2 submicroscopic deletions in myeloproliferative neoplasms.

作者信息

Bartalucci Niccolò, Tarantino Danilo, Enderti Alessio, Colazzo Daniele, Guglielmelli Paola, Vannucchi Alessandro M

机构信息

Department of Experimental and Clinical Medicine, Centro di Ricerca e Innovazione Malattie Mieloproliferative (CRIMM), AOU Careggi, University of Florence, Florence, Italy.

出版信息

Leukemia. 2025 Sep;39(9):2308. doi: 10.1038/s41375-025-02716-1.

DOI:10.1038/s41375-025-02716-1
PMID:40702149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12380592/
Abstract
摘要