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病例报告:超声引导下微波消融联合术后放疗及化疗治疗晚期舌癌

Case Report: Ultrasound-guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancer.

作者信息

Wei Ting, Dai Jiulong, Li Tingting, Hu Ziyue, Wang Lu, Li Juan, Zou Jie, Feng Jia, Lu Man

机构信息

Department of Ultrasound Medical Center, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.

出版信息

Front Oncol. 2025 Jul 9;15:1564348. doi: 10.3389/fonc.2025.1564348. eCollection 2025.

Abstract

BACKGROUND

While surgery remains the standard treatment for tongue cancer, it is associated with a range of functional and aesthetic sequelae. Additionally, ultrasound-guided microwave ablation (MWA) represents a promising minimally invasive alternative for patients with poor performance status or those unwilling to undergo surgery.

CASE PRESENTATION

We report a 50-year-old male patient diagnosed with advanced tongue squamous cell carcinoma and cervical lymph node metastases. Microwave ablation was performed using a power setting of 30 W. Contrast-enhanced ultrasound conducted immediately afterward revealed no enhancement in the ablation area. Following the ablation, the patient received adjuvant radiotherapy and chemotherapy. During the procedure, the patient experienced minimal pain and no significant complications. After more than two years of follow-up, no evidence of metastasis or recurrence was observed, and the patient retained normal speech and swallowing functions.

CONCLUSIONS

Ultrasound-guided MWA combined with radiotherapy and chemotherapy offers a safe, effective, and minimally invasive approach to the treatment of advanced tongue cancer.

摘要

背景

虽然手术仍然是舌癌的标准治疗方法,但它会带来一系列功能和美学后遗症。此外,超声引导下微波消融术(MWA)对于身体状况较差或不愿接受手术的患者来说是一种有前景的微创替代方案。

病例报告

我们报告了一名50岁男性患者,被诊断为晚期舌鳞状细胞癌并伴有颈部淋巴结转移。使用30W的功率设置进行微波消融。术后立即进行的超声造影显示消融区域无增强。消融后,患者接受了辅助放疗和化疗。手术过程中,患者疼痛轻微,未出现明显并发症。经过两年多的随访,未观察到转移或复发迹象,患者保留了正常的言语和吞咽功能。

结论

超声引导下的MWA联合放疗和化疗为晚期舌癌的治疗提供了一种安全、有效且微创的方法。

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