Demirkan Arda Kazim, Gerdan Gizem
Department of Psychiatry, Samsun Liv Hospital, Samsun, Türkiye.
Department of Psychology, Division of Clinical Psychology, Izmir Democracy University, Izmir, Türkiye.
Front Psychiatry. 2025 Jul 9;16:1598901. doi: 10.3389/fpsyt.2025.1598901. eCollection 2025.
OBJECTIVE: Fibromyalgia Syndrome (FMS) is a chronic multifaceted condition characterized by widespread musculoskeletal pain, fatigue, cognitive difficulties, and emotional distress, predominantly affecting women. Although psychological factors are frequently implicated, their interrelations remain unclear. Key variables include alexithymia (particularly the difficulty identifying feelings [DIF] subdimension), somatosensory amplification (SSA), and mood symptoms. This study aimed to examine differences in alexithymia, anxiety, depression, and SSA between individuals with FMS and healthy controls, and explore how these variables relate within the FMS group. METHODS: The study included 283 women (mean age = 31.84, SD = 4.02), comprising 142 FMS patients (mean age = 32.20, SD = 4.41) and 141 healthy controls (mean age = 31.48, SD = 3.58). Participants completed self-report measures assessing alexithymia, anxiety, depression, SSA, and functional impairment. Statistical analyses included independent samples t-tests and multivariate analyses of covariance (MANCOVA) to compare groups, and mediation analyses to examine indirect effects of anxiety and depression. RESULTS: The FMS group reported significantly higher levels of anxiety, depression, DIF, and SSA compared to controls. However, after controlling for anxiety and depression, DIF differences were attenuated and SSA differences were no longer statistically significant. Within the FMS group, individuals with high alexithymic traits also exhibited higher SSA and mood symptoms; however, SSA elevations were no longer evident after accounting for anxiety and depression. Mediation analyses revealed that anxiety and depression significantly mediated the relationship between (a) DIF and functional impairment, and (b) SSA and functional impairment. CONCLUSION: Findings underscore the importance of emotional dysregulation and somatic sensitivity in FMS. Anxiety and depression appear to be key pathways linking these psychological traits to functional outcomes. Interventions aimed at improving emotional awareness and regulation may alleviate mood symptoms and enhance daily functioning in individuals with FMS.
目的：纤维肌痛综合征（FMS）是一种慢性多方面病症，其特征为广泛的肌肉骨骼疼痛、疲劳、认知困难和情绪困扰，主要影响女性。尽管心理因素常常被牵连其中，但其相互关系仍不明确。关键变量包括述情障碍（尤其是难以识别情感[DIF]子维度）、躯体感觉放大（SSA）和情绪症状。本研究旨在检查纤维肌痛综合征患者与健康对照者在述情障碍、焦虑、抑郁和躯体感觉放大方面的差异，并探讨这些变量在纤维肌痛综合征组内的相互关系。 方法：该研究纳入了283名女性（平均年龄 = 31.84，标准差 = 4.02），其中包括142名纤维肌痛综合征患者（平均年龄 = 32.20，标准差 = 4.41）和141名健康对照者（平均年龄 = 31.48，标准差 = 3.58）。参与者完成了评估述情障碍、焦虑、抑郁、躯体感觉放大和功能损害的自我报告测量。统计分析包括独立样本t检验和多变量协方差分析（MANCOVA）以比较组间差异，以及中介分析以检验焦虑和抑郁的间接效应。 结果：与对照组相比，纤维肌痛综合征组报告的焦虑、抑郁、DIF和SSA水平显著更高。然而，在控制焦虑和抑郁后，DIF差异减弱，SSA差异不再具有统计学意义。在纤维肌痛综合征组内，具有高度述情障碍特征的个体也表现出更高的SSA和情绪症状；然而，在考虑焦虑和抑郁后，SSA升高不再明显。中介分析显示，焦虑和抑郁显著介导了（a）DIF与功能损害之间的关系，以及（b）SSA与功能损害之间的关系。 结论：研究结果强调了情绪调节障碍和躯体敏感性在纤维肌痛综合征中的重要性。焦虑和抑郁似乎是将这些心理特征与功能结果联系起来的关键途径。旨在提高情绪意识和调节能力的干预措施可能会减轻纤维肌痛综合征患者的情绪症状并增强其日常功能。
Cochrane Database Syst Rev. 2018-9-29
Cochrane Database Syst Rev. 2020-7-1
Cochrane Database Syst Rev. 2016-8-15
Cochrane Database Syst Rev. 2021-2-3
Climacteric. 2024-10
J Affect Disord. 2024-7-15
Noro Psikiyatr Ars. 2022-11-17
Dermatology. 2022
Indian J Psychiatry. 2021
Zotero 插件