Powers J B, Bergondy M L, Matochik J A
Physiol Behav. 1985 Oct;35(4):607-16. doi: 10.1016/0031-9384(85)90149-0.
Male hamsters were tested for copulatory behavior (CB) with receptive females, for investigatory responses to the females' ano-genital region (A/G), and for attraction to female hamster vaginal secretion (FHVS). After castration, the males received Silastic capsules containing one of two doses of testosterone (T), 5 alpha-dihydrotestosterone (DHT), estradiol (E2) or DHT + E2, and the maintenance of their copulatory and chemoinvestigatory responsiveness was assessed during weekly tests for the next month. The major findings were: (1) T thresholds for the maintenance of CB were lower than they were for the maintenance of A/G behavior and FHVS attraction; (2) DHT + E2 or DHT alone were more effective in maintaining A/G and FHVS attraction than was E2 alone; (3) DHT + E2 or DHT alone maintained ejaculatory behavior in some animals but E2 did not; (4) the posttreatment maintenance of normal ejaculation latencies and intromissions to ejaculation shown by intact and T-treated males was not demonstrated by males receiving DHT or DHT + E2. These results are consistent with the hypothesis that copulatory and chemoinvestigatory behaviors may be subserved by distinct neuroendocrine mechanisms in male hamsters.
对雄性仓鼠进行了测试，观察它们与处于接受状态的雌性交配行为（CB）、对雌性肛门生殖器区域（A/G）的探究反应以及对雌性仓鼠阴道分泌物（FHVS）的吸引力。阉割后，雄性仓鼠接受含有两种剂量之一的睾酮（T）、5α-双氢睾酮（DHT）、雌二醇（E2）或DHT + E2的硅橡胶胶囊，并在接下来的一个月每周测试期间评估它们交配和化学探究反应性的维持情况。主要发现如下：（1）维持CB的T阈值低于维持A/G行为和FHVS吸引力的阈值；（2）DHT + E2或单独的DHT在维持A/G和FHVS吸引力方面比单独的E2更有效；（3）DHT + E2或单独的DHT在一些动物中维持射精行为，但E2不能；（4）完整和T处理的雄性所表现出的正常射精潜伏期和插入射精的处理后维持情况，接受DHT或DHT + E2的雄性并未表现出来。这些结果与以下假设一致，即雄性仓鼠的交配和化学探究行为可能由不同的神经内分泌机制支持。
