Pai Sher-Lu, Izzy Manhal, Chieh Alfred Kow Wei, Montasser Iman F, Kemmer Nyingi, Yoon Uzung, Giorgakis Emmanouil, Selzner Nazia, Lunsford Keri E, Becchetti Chiara, Feier Flávia Heinz, Darwish Murad Sarwa, Montenovo Martin, Aguilera Victoria, Andacoglu Oya M
Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Clin Transplant. 2025 Aug;39(8):e70252. doi: 10.1111/ctr.70252.
Although liver transplantation (LT) rates have increased globally, the demand for organs still exceeds the supply. This review highlights cultures with significant influences on organ donation and LT.
We performed a literature search for articles related to cultures, ethnologies, philosophies, policies, religions, socio-economic factors, and other influences affecting organ donation in LT around the world.
There are astonishing similarities between different cultures. In Africa, Asia, and Europe, people often view the postmortem bodies as sacred and believe that their bodies are gifts from "God" or ancestors. To respect the gift of life, to have a chance in reincarnation, or to enjoy life after death, many believe that their bodily sanctity must be preserved. In Asia, Europe, and Latin America, there is a general reluctance to speak about death. Religions also play an important role in people's views on organ donation. Different regions around the world have similar challenges to organ donation, such as misconceptions about organ trafficking, political and economic instability, and a lack of governmental or religious support.
Addressing the complexities of organ donation and LT requires a multifaceted approach. Culturally sensitive education tailored to diverse communities can dispel myths and misconceptions surrounding organ donation. Fostering partnerships between healthcare providers, religious leaders, community organizations, and policymakers can further facilitate open dialogues and promote organ donation as a noble act to save lives.
Similar cultures around the world post challenges for organ donation. Organizations should foster partnerships between healthcare providers, politicians, and religious leaders to promote donation.
