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青光眼手术可及性的地理分布:一项IRIS®注册研究(视力智能研究)分析

Geographic Distribution of Access to Glaucoma Surgery: An IRIS® Registry (Intelligent Research in Sight) Analysis.

作者信息

Lokhande Anagha, Aziz Kanza, Fujita Asahi, Pasquale Louis R, Shen Lucy Q, Friedman David S, Boland Michael V, Lorch Alice C, Miller Joan W, Wang Mengyu, Elze Tobias, Zebardast Nazlee

机构信息

Harvard Ophthalmology AI Lab, Schepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, Massachusetts; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Eye and Vision Research Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

Department of Ophthalmology, Mass Eye and Ear, Harvard Medical School, Boston, Massachusetts.

出版信息

Ophthalmology. 2025 Jul 22. doi: 10.1016/j.ophtha.2025.07.011.

Abstract

PURPOSE

We evaluated access to glaucoma surgical care by quantifying the geographic distribution of glaucoma surgeries across the United States.

DESIGN

Retrospective cohort study.

PARTICIPANTS

Using the IRIS® Registry (Intelligent Research in Sight), we extracted patient information associated with all glaucoma procedures from January 1, 2013, to December 31, 2019.

METHODS

Descriptive statistics were used to evaluate physician, patient travel, and practice patterns. The US Department of Agriculture's Rural-Urban Commuting Area Codes were used to define urban and nonurban zip codes. Multivariate logistic regression analyses were performed to determine which types of glaucoma surgeries were more likely to occur in urban areas. According to US Postal Service definitions, districts were defined as aggregates of zip codes sharing the same first 3 digits; regions shared the same initial digit.

MAIN OUTCOME MEASURES

The primary outcomes were the likelihood of each procedure type occurring in urban areas. The secondary outcomes were procedure characteristics (e.g., type, location) and the proportion of procedures requiring inter-region or inter-district travel.

RESULTS

The most performed glaucoma procedures were trabecular microbypass (iStent and Hydrus) (207 451 cases, 39%) and trabeculectomy (115 302 cases, 22%). Urban practice locations accounted for most surgeries (91%), with 96% of glaucoma subspecialists and 88% of nonglaucoma ophthalmologists performing surgeries exclusively in urban areas. Among 281 271 surgeries requiring inter-district travel (47%), most were performed in urban, rather than nonurban, practices (93%). A smaller subset of 42 667 surgeries involved inter-region travel (8% across all procedure types). Trabeculectomy (11%) and glaucoma drainage device (GDD) implantation (10%) were the procedures with their highest proportion of cases involving inter-region travel. We found higher odds of nearly all types of glaucoma surgeries occurring in urban practice locations: goniotomy/canaloplasty (odds ratio [OR], 1.66; confidence interval [CI], 1.59-1.74), XEN ab interno (OR, 1.54; CI, 1.38-1.72), endocyclophotocoagulation (OR, 1.46; CI, 1.39-1.53), GDD (OR, 1.70; CI, 1.62-1.77), and trabeculectomy (OR, 1.24; CI, 1.17-1.32). Only trabecular microbypass was less likely to be performed in urban areas (OR, 0.49; CI, 0.47-0.51).

CONCLUSIONS

Patients are more likely to receive most types of glaucoma surgeries in urban practice locations. Trabeculectomy or GDD implantation involved inter-regional travel in approximately 10% of cases.

FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found after the references.

摘要

目的

我们通过量化美国青光眼手术的地理分布来评估青光眼手术治疗的可及性。

设计

回顾性队列研究。

参与者

利用IRIS®注册系统(智能视力研究),我们提取了2013年1月1日至2019年12月31日期间所有青光眼手术相关的患者信息。

方法

采用描述性统计来评估医生、患者就诊行程及医疗模式。美国农业部的城乡通勤区号用于定义城市和非城市邮政编码。进行多因素逻辑回归分析以确定哪些类型的青光眼手术更可能在城市地区进行。根据美国邮政服务的定义,地区被定义为前三位数字相同的邮政编码集合;区域共享相同的首位数字。

主要观察指标

主要结局是每种手术类型在城市地区发生的可能性。次要结局是手术特征(如类型、地点)以及需要跨区域或跨地区就诊的手术比例。

结果

实施最多的青光眼手术是小梁微旁路手术(iStent和Hydrus)(207451例,占39%)和小梁切除术(115302例,占22%)。城市医疗机构进行了大多数手术(91%),96%的青光眼专科医生和88%的非青光眼眼科医生仅在城市地区进行手术。在281271例需要跨地区就诊的手术中(占47%),大多数手术是在城市而非非城市医疗机构进行的(93%)。一小部分42667例手术涉及跨区域就诊(在所有手术类型中占8%)。小梁切除术(11%)和青光眼引流装置(GDD)植入术(10%)是跨区域就诊病例比例最高的手术。我们发现几乎所有类型的青光眼手术在城市医疗机构进行的可能性更高:前房角切开术/房角成形术(优势比[OR],1.66;置信区间[CI],1.59 - 1.74),XEN内路植入术(OR,1.54;CI,1.38 - 1.72),睫状体光凝术(OR,1.46;CI,1.39 - 1.53),GDD植入术(OR,1.70;CI,1.62 - 1.77),以及小梁切除术(OR,1.24;CI,1.17 - 1.32)。只有小梁微旁路手术在城市地区进行的可能性较小(OR,0.49;CI,0.47 - 0.51)。

结论

患者在城市医疗机构更有可能接受大多数类型的青光眼手术。小梁切除术或GDD植入术约10%的病例涉及跨区域就诊。

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