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[近距离放射治疗源的刚性体模剂量测定,特别涉及碘-125]

[Rigid phantom dosimetry of brachytherapy sources, with special reference to 125-I].

作者信息

Arcovito G, Piermattei A, Bacci C, Pittella G, Castagnola M

出版信息

Radiol Med. 1985 Jun;71(6):426-32.

PMID:4070702
Abstract

At present, the brachytherapy dosimetry requires the highest level of accuracy in determining the physical parameters of many different radiation sources. Brachytherapy sources differ not only in the nucleus (widely ranging between 30 keV and 1 MeV), but also in the strength and geometrical and filtration characteristics. This work reports the brachytherapy dosimetry carried out in a rigid perspex phantom which allows measurements by means of solid state dosimeters (TLD, semiconductor), ionization chamber and film. Film densities were measured by means of a computerized Perkin-Elmer 1010G microdensitometer, with a spatial resolution of 50 microns. The isodensity lines were dose calibrated by TLD measurements. The dosimetry of the 125I, 192Ir and 198Au sources is reported. The dose distributions of the low energy 125I source, in two different tissues (muscle and adipose) were studied, by means of laboratory built tissue-equivalent sections of the phantoms. The experimental data suggest that this dosimetric procedure is suitable for intercomparison measurements between different radiotherapy centers using the same nuclides in different sources.

摘要

目前,近距离放射治疗剂量测定在确定许多不同辐射源的物理参数时需要最高水平的准确性。近距离放射治疗源不仅在核素方面存在差异(范围广泛,在30keV至1MeV之间),而且在强度、几何形状和过滤特性方面也有所不同。这项工作报告了在刚性有机玻璃模体中进行的近距离放射治疗剂量测定,该模体允许使用固态剂量计(热释光剂量计、半导体剂量计)、电离室和胶片进行测量。胶片密度通过计算机化的珀金埃尔默1010G微密度计进行测量,空间分辨率为50微米。等密度线通过热释光剂量计测量进行剂量校准。报告了125I、192Ir和198Au源的剂量测定。通过实验室制作的模体组织等效切片,研究了低能125I源在两种不同组织(肌肉和脂肪)中的剂量分布。实验数据表明,这种剂量测定程序适用于不同放疗中心之间使用不同源中相同核素的相互比较测量。

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