Garcia-Garcia Hector M, Sanz-Sanchez Jorge, Pinilla-Echeverri Natalia, Blanco Pablo J, Bourantas Christos, Alfonso Fernando
Interventional Cardiology, MedStar Washington Hospital Center, Washington, D.C., USA.
Hospital Universitari i Politecnic La Fe, Valencia, Spain.
EuroIntervention. 2025 Jul 21;21(14):e778-e795. doi: 10.4244/EIJ-D-24-00387.
Atherosclerosis is a complex disease with multiple factors associated with its progression and complications.Fibroatheroma is a pathological entity which contains abundant lipid, and often, a thin fibrous cap that is the most common underlying cause of acute myocardial infarction. Based on pathological descriptions, we propose a new imaging-based nomenclature indicating high-risk plaque characteristics that can be identified with imaging. Additionally, we review the literature indicating in vivo plaque characterisation as well as outlining the natural history of plaques and, more importantly, its responses to systemic and local therapies. Intravascular imaging has positively impacted how we evaluate atherosclerosis, and it can provide guidance on the use of tailored therapies and the evaluation of their long-term follow-up effects.
动脉粥样硬化是一种复杂的疾病，有多种因素与其进展和并发症相关。纤维粥样瘤是一种病理实体，含有丰富的脂质，且通常有一层薄纤维帽，这是急性心肌梗死最常见的潜在病因。基于病理描述，我们提出一种新的基于影像学的命名法，用以表明可通过影像学识别的高危斑块特征。此外，我们回顾了相关文献，这些文献阐述了斑块的体内特征，概述了斑块的自然病程，更重要的是，还阐述了其对全身和局部治疗的反应。血管内成像对我们评估动脉粥样硬化产生了积极影响，它可为使用定制化治疗以及评估其长期随访效果提供指导。
