Pourzinal Dana, Brooks Deborah, Sriram Deepa, Mitchell Leander K, Pachana Nancy A, Shrubsole Kirstine, Wood Brian, O'Sullivan John D, Marsh Rodney, Lehn Alexander, Liddle Jacki, Tan Edwin C K, Halford W Kim, Page Neil, Dissanayaka Nadeeka N
UQ Centre for Clinical Research The University of Queensland Herston Queensland Australia.
School of Psychology The University of Queensland Saint Lucia Queensland Australia.
Alzheimers Dement (Amst). 2025 Jul 24;17(3):e70152. doi: 10.1002/dad2.70152. eCollection 2025 Jul-Sep.
Variations in clinical management of cognitive disorders in Parkinson's disease (PD) can delay diagnosis, treatment, and care. To harmonize clinical practice, we aimed to gain consensus on best practice recommendations for the diagnosis, evaluation, and management of cognitive disorders in PD.
Fifty-eight evidence-based recommendations were presented to an expert panel ( = 29) of Australian PD clinicians and researchers using a modified Delphi approach to gauge agreement. A 5-point Likert scale was used, with a median score > 4 and inter-quartile range < 1, indicating satisfactory agreement. Optional written feedback was also collected. A steering committee of clinicians, researchers, and lived experience experts ( = 13) revised recommendations based on panel feedback.
Fifty-one evidence-based and expert-endorsed recommendations for the diagnosis, evaluation, and management of cognitive disorders in PD were produced.
The recommendations serve as a foundational framework to guide clinical practice for cognitive disorders in PD and improve the provision of care.
Recommendations for cognitive disorders in Parkinson's disease were developed.Diagnosis, evaluation, and management of cognitive disorders were explored.A modified Delphi approach was used.A panel of 29 Australian clinician and/or research experts provided input.Fifty-one evidence-based and expert-backed recommendations were developed.
帕金森病（PD）认知障碍临床管理的差异可能会延迟诊断、治疗和护理。为了使临床实践标准化，我们旨在就PD认知障碍的诊断、评估和管理的最佳实践建议达成共识。
采用改良的德尔菲法，向由29名澳大利亚PD临床医生和研究人员组成的专家小组提出了58条基于证据的建议，以评估一致性。使用5点李克特量表，中位数得分>4且四分位间距<1表示达成满意的共识。还收集了可选的书面反馈。由临床医生、研究人员和有实际经验的专家（共13人）组成的指导委员会根据专家小组的反馈修订了建议。
制定了51条关于PD认知障碍诊断、评估和管理的基于证据且得到专家认可的建议。
这些建议作为一个基础框架，以指导PD认知障碍的临床实践并改善护理服务。
制定了帕金森病认知障碍的建议。探讨了认知障碍的诊断、评估和管理。采用了改良的德尔菲法。由29名澳大利亚临床医生和/或研究专家组成的小组提供了意见。制定了51条基于证据且得到专家支持的建议。
