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股骨前交叉韧带足迹区域内骨道入口选择对兔近等长前交叉韧带重建效果的影响

The impact of bone channel entrance selection within the footprint region of the femoral anterior cruciate ligament on the achievement of near isometric ACL reconstruction in rabbits.

作者信息

Zhang Jiating, Xu Chengfeng, Wang Jiangtao, Zhang Jia, Zhao Gang, Liu Liu, Li Chunbao, Liu Yujie

机构信息

Emergency Surgery Department, The Third Medical Center of Chinese PLA General Hospital, Beijing, China.

School of Graduate Studies, Chinese PLA Medical School, Beijing, China.

出版信息

Front Surg. 2025 Jul 10;12:1571180. doi: 10.3389/fsurg.2025.1571180. eCollection 2025.

Abstract

INTRODUCTION

Construction of an animal model of rabbit anterior cruciate ligament (ACL) near isometric reconstruction is a basic condition to study the patterns of graft stress and tendon to bone healing. The impact of alterations in the bone tunnel entrance within the femoral footprint region on graft tension remains uncertain. The objective of this study was to determine the femoral tunnel entrance that provides the closest approximation to near-isometric reconstruction within the femoral ACL footprint.

MATERIALS AND METHODS

Eighteen Cadaveric rabbit knees were used in this experiment. The semitendinosus autografts were employed for ACL reconstruction. Six knees were reconstructed using the middle position of the femoral footprint area as the entrance (Mi-tunnel), six knees used a position 2 mm anterior to the middle (An-tunnel), and six knees used a position 2 mm posterior to the middle (Po-tunnel). All grafts were pretensioned with 10 N at 150° and 90° flexion and firmly fixed at the tibial end. The change in graft strain was measured under maximum flexion and extension in the rabbit knee joints.

RESULTS

Under a maximum flexion of 150° and 10 N pretension, the graft strain decreased significantly during knee extension in the An-tunnel and Mi-tunnel groups and there was no significant decrease in the Po-tunnel group. There were significant differences in graft strain between the Po-tunnel and An-tunnel during knee extension at 135°-35° ( < 0.05). Under 90° flexion and 10 N pretension, the Po-tunnel group showed a minimal change in graft strain compared to the An-tunnel and Mi-tunnel groups with knee extension and flexion (135°-35°) except at the initial pretension Angle. There was a statistically significant difference in graft tension when the Po-tunnel compared to the An-tunnel ( < 0.05).

CONCLUSIONS

The Po-tunnel within the femoral footprint region may be the best choice for ACL near isometric reconstruction in rabbits.

摘要

引言

构建兔前交叉韧带(ACL)近等长重建的动物模型是研究移植物应力模式和腱骨愈合的基本条件。股骨足迹区域内骨隧道入口的改变对移植物张力的影响尚不确定。本研究的目的是确定在股骨ACL足迹内最接近近等长重建的股骨隧道入口。

材料与方法

本实验使用了18个兔尸体膝关节。采用半腱肌自体移植物进行ACL重建。6个膝关节以股骨足迹区域的中间位置作为入口进行重建(中间隧道组),6个膝关节以中间位置前方2 mm处作为入口(前方隧道组),6个膝关节以中间位置后方2 mm处作为入口(后方隧道组)。所有移植物在150°和90°屈曲时用10 N预张紧,并在胫骨端牢固固定。在兔膝关节最大屈伸时测量移植物应变的变化。

结果

在最大屈曲150°和10 N预张紧下,前方隧道组和中间隧道组在膝关节伸展过程中移植物应变显著降低,而后方隧道组没有显著降低。在膝关节伸展135°-35°时,后方隧道组和前方隧道组之间的移植物应变存在显著差异(<0.05)。在90°屈曲和10 N预张紧下,与前方隧道组和中间隧道组相比,后方隧道组在膝关节伸展和屈曲(135°-35°)时除初始预张紧角度外,移植物应变变化最小。后方隧道组与前方隧道组相比,移植物张力存在统计学显著差异(<0.05)。

结论

股骨足迹区域内的后方隧道可能是兔ACL近等长重建的最佳选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3244/12286926/d3653d0f5e27/fsurg-12-1571180-g001.jpg

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