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髋部骨折手术区域麻醉使用的时间趋势:一项回顾性单中心研究

Temporal Trends in the Use of Regional Anesthesia for Hip Fracture Surgery: A Retrospective Single-Center Study.

作者信息

Kukielski Casey J, Deiling Brittany L, Naik Bhiken I, Reon Brian J, Yarboro Seth R, Elkassabany Nabil

机构信息

Anesthesiology, Wellstar Kennestone Hospital, Marietta, USA.

Anesthesiology, University of Virginia Health System, Charlottesville, USA.

出版信息

Cureus. 2025 Jun 24;17(6):e86636. doi: 10.7759/cureus.86636. eCollection 2025 Jun.

Abstract

INTRODUCTION

Hip fractures are associated with significant morbidity and mortality in the United States. Over the past decade, considerable research has been directed toward identifying the optimal anesthetic and analgesic techniques for hip fracture surgery. It was hypothesized that regional anesthesia (neuraxial anesthesia and peripheral nerve blocks) may improve outcomes by avoiding the risks of general anesthesia and providing opioid-sparing analgesia in these complex patients. For neuraxial anesthesia, evidence of clinical benefit has been inconsistent in the literature; however, studies on peripheral nerve block analgesia have shown more consistent advantages. It is unclear if this data has influenced changes in clinical practice.

MATERIALS AND METHODS

We conducted a retrospective single-center study of patients who underwent hip fracture surgery at the University of Virginia Medical Center from 2018 to 2022. Descriptive statistics were produced for patient demographics and clinical characteristics, and generalized linear regression models were used to examine trends in anesthetic techniques (general versus neuraxial anesthesia and use of peripheral nerve blocks) over time. We also examined the association between regional anesthesia and patient outcomes, including hospital length of stay (primary outcome), postoperative pain scores, incidence of acute kidney injury and myocardial injury, and discharge disposition (secondary outcomes), as well as diurnal variation in regional anesthesia utilization.

RESULTS

We observed a 30% increase in the number of neuraxial anesthesia cases per year (from 10% (n = 12) of patients in 2018 to 33% (n = 40) in 2022), as well as an increase in peripheral nerve block utilization over time (1.7% (n = 2) of patients in 2018 to 28.1% (n = 34) in 2022). Neuraxial anesthesia was associated with a 17.1% lower hospital length of stay compared to general anesthesia (primary outcome, mean 6.2 vs 7.4 days, p = 0.006). There were no other differences in postoperative outcomes, and there was no evidence of diurnal variation in regional anesthesia utilization.

CONCLUSIONS

The increase in peripheral nerve block utilization demonstrates continued progress in quality of care, while emphasizing that there is still significant room for improvement. A larger multicenter database study will be helpful to assess if the evolving literature has influenced broader changes in clinical practice.

摘要

引言

在美国,髋部骨折与显著的发病率和死亡率相关。在过去十年中,大量研究致力于确定髋部骨折手术的最佳麻醉和镇痛技术。据推测,区域麻醉(神经轴索麻醉和外周神经阻滞)可能通过避免全身麻醉的风险并为这些复杂患者提供阿片类药物节省型镇痛来改善预后。对于神经轴索麻醉,文献中临床益处的证据并不一致;然而,关于外周神经阻滞镇痛的研究显示出更一致的优势。尚不清楚这些数据是否影响了临床实践的变化。

材料与方法

我们对2018年至2022年在弗吉尼亚大学医学中心接受髋部骨折手术的患者进行了一项回顾性单中心研究。对患者人口统计学和临床特征进行了描述性统计,并使用广义线性回归模型来研究麻醉技术(全身麻醉与神经轴索麻醉以及外周神经阻滞的使用)随时间的趋势。我们还研究了区域麻醉与患者预后之间的关联,包括住院时间(主要结局)、术后疼痛评分、急性肾损伤和心肌损伤的发生率以及出院处置(次要结局),以及区域麻醉使用的日变化。

结果

我们观察到每年神经轴索麻醉病例数增加30%(从2018年的10%(n = 12)患者增加到2022年的33%(n = 40)),并且随着时间的推移外周神经阻滞的使用率也有所增加(从2018年的1.7%(n = 2)患者增加到2022年的28.1%(n = 34))。与全身麻醉相比,神经轴索麻醉使住院时间缩短了17.1%(主要结局,平均6.2天对7.4天,p = 0.006)。术后结局没有其他差异,并且没有证据表明区域麻醉使用存在日变化。

结论

外周神经阻滞使用率的增加表明护理质量持续进步,同时强调仍有很大的改进空间。一项更大规模的多中心数据库研究将有助于评估不断发展的文献是否影响了临床实践的更广泛变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d73e/12287677/1af9a996a94a/cureus-0017-00000086636-i01.jpg

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