AlQahtani Sarah M, Alabdulaal Maria R, Aljubran Hussain J, Almomen Ali
Department of Otolaryngology Head and Neck Surgery, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.
Department of Otolaryngology Head and Neck Surgery, Aljabr Eye and ENT Hospital, Alahsa Health Cluster, Alahsa 36375, Saudi Arabia.
J Surg Case Rep. 2025 Jul 24;2025(7):rjaf556. doi: 10.1093/jscr/rjaf556. eCollection 2025 Jul.
Solitary fibrous tumors (SFT) are rare spindle cell neoplasms of mesenchymal origin, typically occurring in the pleura, with extra-pleural manifestations being uncommon. SFTs of the nasal cavity are particularly rare, with limited cases documented in the literature. This report presents the case of a 62-year-old female with a solitary fibrous tumor arising from the nasal septum. The patient presented with a unilateral nasal mass, obstruction, and nasal discharge, which did not improve with antibiotics. The tumor was successfully excised via an endonasal endoscopic approach, and histopathological analysis confirmed the diagnosis of an SFT with positive CD34 and CD99 markers. The patient remained symptom-free with no recurrence over 2 years of follow-up. This case highlights the importance of considering SFTs in the differential diagnosis of nasal masses and underscores the effectiveness of endonasal endoscopic resection as a minimally invasive treatment approach.
孤立性纤维瘤（SFT）是一种罕见的间叶源性梭形细胞肿瘤，通常发生于胸膜，胸膜外表现不常见。鼻腔孤立性纤维瘤尤为罕见，文献记载的病例有限。本报告介绍了一名62岁女性鼻中隔孤立性纤维瘤的病例。患者表现为单侧鼻腔肿物、鼻塞和流涕，使用抗生素治疗无效。通过鼻内镜手术成功切除肿瘤，组织病理学分析确诊为SFT，CD34和CD99标记物呈阳性。患者随访2年无症状复发。该病例强调了在鼻腔肿物鉴别诊断中考虑SFT的重要性，并强调了鼻内镜切除术作为一种微创治疗方法的有效性。
