El Ghaffouli Sara, Khmou Mouna, El Beyeg Manal, El Graini Soumya, Latib Rachida, Mahdi Youssef, El-Khannoussi Basma
Department of Pathology of the National Institute of Oncology, Ibn Sina University Hospital Center, Allal Al Fassi Avenue, Rabat 10100, Morocco.
Faculty of Medicine and Pharmacy, Mohammed V University, Mohamed Belarbi Alaoui Avenue, Rabat 10000, Morocco.
J Surg Case Rep. 2025 Jul 24;2025(7):rjaf555. doi: 10.1093/jscr/rjaf555. eCollection 2025 Jul.
Adenocarcinoma constitutes 90%-95% of all malignant gallbladder (GB) neoplasms, making it the predominant subtype. In contrast, adenosquamous carcinoma (ASC) is significantly less common and comprises both glandular and squamous components. This subtype is more aggressive and has a worse prognosis than GB adenocarcinoma. Currently, complete surgical resection remains the cornerstone of treatment. In this paper, we present the case of a 56-year-old female diagnosed with moderately differentiated ASC of the GB, who underwent radical cholecystectomy, including the resection of liver segments IVb and V.
腺癌占所有恶性胆囊肿瘤的90%-95%，是主要的亚型。相比之下，腺鳞癌（ASC）明显少见，由腺性和鳞状成分组成。这种亚型比胆囊腺癌侵袭性更强，预后更差。目前，完整的手术切除仍然是治疗的基石。在本文中，我们报告了一例56岁女性被诊断为胆囊中分化ASC的病例，该患者接受了根治性胆囊切除术，包括切除肝IVb段和V段。
