Grenman R, Salo H, Rintala A
Scand J Plast Reconstr Surg. 1985;19(2):215-9. doi: 10.3109/02844318509072379.
Nine midline sinuses of the upper lip in eight patients have been described previously. They have been located from the skin under the columella to the frenulum, and have always been directed towards the frenulum. Three new cases are presented: a sinus reaching from the skin of the philtrum to the frenulum in a child with Pierre Robin syndrome, another one in the frenulum of a patient with two separate midline sinuses of the nose, and a third in the frenulum of a child with a partial median cleft lip. The midline sinus is probably caused by disturbed development of the nasofrontal process. The combination of upper lip sinus and Pierre Robin's syndrome is hardly coincidental and supports the concept that the latter is not caused solely by a foetal malposition.
先前已描述过8例患者上唇的9个中线窦。它们位于鼻小柱下方的皮肤至系带之间,且总是朝向系带。现报告3例新病例:1例患有皮埃尔·罗宾综合征的儿童,其鼻窦从人中皮肤延伸至系带;另1例患有双侧鼻中线窦的患者,其鼻窦位于系带处;第3例是1例患有部分正中唇裂的儿童,其鼻窦位于系带处。中线窦可能是由鼻额突发育紊乱引起的。上唇窦与皮埃尔·罗宾综合征的并发并非偶然,这支持了后者并非仅由胎儿胎位异常引起的观点。