Martinez Rivera Carlos, Hernandez Biette Agnes, Núñez Condominas Anna, Garcia Olive Ignasi, Basagaña Torrentó María, Padró Casas Clara, Tapia Barredo Leandro, Rosell Gratacós Antoni
Pneumology Department, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.
Allergology Section, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.
Clin Pract. 2025 Jun 24;15(7):116. doi: 10.3390/clinpract15070116.
: This study evaluates the adherence to guidelines for the management of asthma exacerbations in the ED, recommendations at discharge, and impact at a 1-year of follow-up. : An observational study of 87 asthma patients who attended the ED during 2022 and were discharged within 24 h was carried out. Data before the ED admission, care in the ED, and discharge reports, as well as the clinical characteristics at follow-up, were recorded. The relationship between complete ED discharge reports and outcome at 1 year, and factors associated with new exacerbations were analyzed. : The mean age was 51 years, 80% of the patients were women, and 50% had severe asthma. Prior to ED admission, 58.8% of patients used ICS-LABA, 26.2% triple therapy, 31.8% had not been treated, and 51.2% had presented at least one exacerbation. On ED admission, PEF was measured in 21% of patients only, decreasing to 6.8% at 3 h. In the ED discharge reports, the use of systemic corticosteroids was recommended in 76.5% of the cases and ICS-LABA in 46.9%. However, complete ED discharge reports were recorded for only 18.2% of patients. A total of 6.7% of patients were referred to a primary care physician and 29.9% to a pneumologist. Complete ED discharge forms did not improve asthma control at follow-up or reduce new exacerbations. Exacerbations before ED admission (OR 2.49, 95% CI 1.47-4.22, = 0.001) and the use of any asthma controller treatment (OR 1.84, 95% CI 1.84-507, = 0.017) were associated with ≥2 exacerbations at follow-up. : Contact with ED did not improve disease control or reduce exacerbations. It is necessary to optimize care before, during, and after exacerbations by developing integrated programs with primary care to improve asthma management.
本研究评估了急诊科哮喘急性加重管理指南的遵循情况、出院建议以及1年随访的影响。对2022年期间到急诊科就诊并在24小时内出院的87例哮喘患者进行了一项观察性研究。记录了急诊科入院前的数据、急诊科的治疗情况、出院报告以及随访时的临床特征。分析了完整的急诊科出院报告与1年结局之间的关系以及与新的急性加重相关的因素。平均年龄为51岁,80%的患者为女性,50%患有重度哮喘。在急诊科入院前,58.8%的患者使用吸入性糖皮质激素-长效β2受体激动剂(ICS-LABA),26.2%使用三联疗法,31.8%未接受治疗,51.2%至少出现过一次急性加重。在急诊科入院时,仅21%的患者测量了呼气峰流速(PEF),3小时时降至6.8%。在急诊科出院报告中,76.5%的病例建议使用全身糖皮质激素,46.9%建议使用ICS-LABA。然而,仅18.2%的患者有完整的急诊科出院报告。共有6.7%的患者被转诊至初级保健医生,29.9%被转诊至肺科医生。完整的急诊科出院表格在随访时并未改善哮喘控制或减少新的急性加重。急诊科入院前的急性加重(比值比[OR]2.49,95%置信区间[CI]1.47 - 4.22,P = 0.001)和使用任何哮喘控制药物治疗(OR 1.84,95% CI 1.84 - 507,P = 0.017)与随访时≥2次急性加重相关。与急诊科的接触并未改善疾病控制或减少急性加重。有必要通过制定与初级保健相结合的综合项目来优化急性加重前、期间和之后的治疗,以改善哮喘管理。