Daravigka Alexandra, Ninis Stefanos, Bourdekas Panagiotis, Konstantinidis Alexandros O, Ginoudis Argyrios, Adamama-Moraitou Katerina K, Lyraki Maria, Soubasis Nektarios
Companion Animal Clinic (Medicine Unit), School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece.
Private Practice, 54454 Thessaloniki, Greece.
Vet Sci. 2025 Jun 20;12(7):604. doi: 10.3390/vetsci12070604.
A five-month-old female mixed-breed dog presented with a two-week history of polyuria, polydipsia, and vomiting. Clinical examination revealed poor body condition, growth retardation, pale oral mucous membranes, weak pulse, and prolonged capillary refill time. Laboratory findings included neutrophilic leukocytosis with a regenerative left shift, fasting hyperglycemia, elevated fructosamine, glycated hemoglobin, and β-hydroxybutyrate concentrations, while the acid-base balance remained normal. Canine-specific pancreatic lipase and trypsin-like immunoreactivity concentrations ruled out an underlying pancreatitis or exocrine pancreatic insufficiency, respectively. Urinalysis showed glycosuria and ketonuria. Supportive care included antibiotics and regular insulin administration. Abdominal ultrasonography identified a pancreatic cavity with a thick wall and mixed echogenic fluid. Ultrasound-guided drainage was performed without complications. Cytology confirmed a pancreatic abscess with pyogranulomatous inflammation, though the culture results were negative. The dog was discharged with intermediate-acting lente insulin. Follow-up ultrasonographic evaluations at 7, 14, and 21 days and 5 months post-drainage showed no recurrence. The diabetes remained well-controlled one year post-discharge. This case report describes the successful management of a dog with juvenile diabetes mellitus complicated by a pancreatic abscess, highlighting the effectiveness of percutaneous ultrasound-guided drainage combined with medical therapy.
一只五个月大的雌性混血犬出现了两周的多尿、多饮和呕吐病史。临床检查发现身体状况不佳、生长发育迟缓、口腔黏膜苍白、脉搏微弱以及毛细血管再充盈时间延长。实验室检查结果包括中性粒细胞增多伴再生性左移、空腹血糖升高、果糖胺、糖化血红蛋白和β-羟基丁酸浓度升高，而酸碱平衡保持正常。犬特异性胰脂肪酶和胰蛋白酶样免疫反应性浓度分别排除了潜在的胰腺炎或外分泌性胰腺功能不全。尿液分析显示糖尿和酮尿。支持性治疗包括使用抗生素和定期注射胰岛素。腹部超声检查发现一个壁厚且有混合回声液的胰腺腔。在超声引导下进行了引流，未出现并发症。细胞学检查证实为伴有脓性肉芽肿性炎症的胰腺脓肿，尽管培养结果为阴性。该犬使用中效胰岛素Lente出院。在引流后7天、14天、21天和5个月进行的超声随访评估显示无复发。出院一年后糖尿病仍得到良好控制。本病例报告描述了一只患有青少年糖尿病并发胰腺脓肿的犬的成功治疗，突出了经皮超声引导引流联合药物治疗的有效性。
