Mello Sheila Santana de, Avila Fagundes Aracelle Alves de, Mota Francisco C D, Ronchi Alessandra A M
Graduate Program in Veterinary Medicine, Federal University of Uberlândia, BR-050, KM 78, Glória Campus, Block 1CCG, Uberlândia 38410-337, MG, Brazil.
Companion Animal Surgical Clinic Division, Veterinary Hospital, Federal University of Uberlândia, 3289 Mato Grosso Avenue, Umuarama Campus, Uberlândia 38405-314, MG, Brazil.
Vet Sci. 2025 Jul 2;12(7):631. doi: 10.3390/vetsci12070631.
Mammary tumors are the most common neoplasms in female dogs, with mastectomy being the primary treatment. The impact of mastectomy type on survival remains unclear. This study evaluated the effect of different surgical techniques on the survival of female dogs with mammary carcinomas. A total of 307 dogs with 734 mammary tumors were analyzed. Ages ranged from 1 to 17 years, with mixed breeds comprising 48.9%. Most tumors (92.9%) were malignant, predominantly carcinoma in a mixed tumor (30.2%). Unilateral mastectomy was the most common technique (65.8%). Lumpectomy showed the shortest mean survival (179 days) and was associated with a 4.9-fold increased risk of death ( = 0.009). There was no significant association between surgical technique and overall survival or recurrence of mammary carcinoma ( = 0.2). This study relied on owner-reported data for survival and tumor recurrence. Lumpectomy appears to be associated with shorter survival times in female dogs with mammary carcinoma. Therefore, it may be advisable to reconsider this technique as a primary treatment option.
乳腺肿瘤是雌性犬类中最常见的肿瘤，乳房切除术是主要的治疗方法。乳房切除术类型对生存的影响尚不清楚。本研究评估了不同手术技术对患有乳腺癌的雌性犬类生存的影响。共分析了307只患有734个乳腺肿瘤的犬。年龄范围为1至17岁，混种犬占48.9%。大多数肿瘤（92.9%）为恶性，主要是混合瘤中的癌（30.2%）。单侧乳房切除术是最常见的技术（65.8%）。肿块切除术的平均生存期最短（179天），死亡风险增加4.9倍（P = 0.009）。手术技术与乳腺癌的总体生存或复发之间无显著关联（P = 0.2）。本研究依赖于主人报告的生存和肿瘤复发数据。肿块切除术似乎与患有乳腺癌的雌性犬的较短生存时间相关。因此，可能有必要重新考虑将该技术作为主要治疗选择。
