Weiss P A, Winter R
Geburtshilfe Frauenheilkd. 1977 Jul;37(7):615-8.
The estriol 16-glucuronid excretion was determined in 186 urine samples in cases with preeclampsia, post maturity, pregnancies past the expected date of confinement, intra-uterine fetal deaths, congenital anomalies, Rhesus incompatability and diabetes mellitus. In groups with mild dystrophy, severe dystrophy, and intra-uterine fetal death, three zones of estriol 16-glucuronid excretion were determined. Zone 1 is suggestive of a possible fetal impairment. Zone 2 shows a high probability of fetal impairment and Zone 3 was considered as lethal zone suggestive of imminent intra-uterine fetal death. The degree of rhesus incompatability, disease of the fetus or of diabetogenic fetopathy was not recognizable by the estriol 16-glucuronid excretion.
对186例患有先兆子痫、过期成熟、妊娠超过预产期、宫内死胎、先天性畸形、恒河猴血型不相容和糖尿病的孕妇的尿液样本进行了雌三醇16 - 葡萄糖醛酸苷排泄量测定。在轻度营养不良、重度营养不良和宫内死胎组中,确定了雌三醇16 - 葡萄糖醛酸苷排泄的三个区域。区域1提示可能存在胎儿损伤。区域2显示胎儿损伤的可能性很高,区域3被认为是致死区,提示即将发生宫内死胎。恒河猴血型不相容程度、胎儿疾病或致糖尿病性胎儿病无法通过雌三醇16 - 葡萄糖醛酸苷排泄来识别。